Application Notes: LC

An easy and sensitive method to analyze Aflatoxins B1, B2, G1, G2 and Ochratoxin A in cannabis plant and edible products at levels below established by state regulations.

A sensitive HPLC method allows analyzing cannabinoids, including THC and CBD, in hemp and hemp-containing products to ensure compliance with the 2018 Farm Bill.

This application note demonstrates the development of an SFC separation method for 46 highly polar compounds on different columns using an increased amount of modifier.

This technical overview presents the measurement of the instrument detection limit (IDL) at two different conditions of MRM dwell times.

The applicability of AF4-UV-MALS for sizing and quantification of adeno-associated virus (AAV) samples with different degrees of aggregation is presented.

This study investigates the capabilities of asymmetrical flow field-flow fractionation coupled with MALS for the detection of carbon nanotubes in soot and soil.

The applicability of AF4-UV-MALS for sizing and quantification of adeno-associated virus (AAV) samples with different degrees of aggregation is presented.

This study investigates the capabilities of asymmetrical flow field-flow fractionation coupled with MALS for the detection of carbon nanotubes in soot and soil.

This study demonstrates the combination of inverse supercritical fluid extraction and miniaturized AF4-MALS for the analysis of nanoparticles in commercial sunscreens.

This study describes the analysis of PLGA particles under physiological conditions using centrifugal field-flow fractionation coupled with dynamic light scattering.

This study describes the analysis of PLGA particles under physiological conditions using centrifugal field-flow fractionation coupled with dynamic light scattering.

This study describes the separation of nanoplastics and determination of their surface charge by electrical asymmetrical flow field-flow fractionation.

This study describes the separation of nanoplastics and determination of their surface charge by electrical asymmetrical flow field-flow fractionation.

Electrical asymmetrical flow field-flow fractionation coupled with MALS was used to characterize the NIST monoclonal antibody reference material 8671.

This application note presents the characterization of ribosomal RNA using asymmetrical flow field-flow fractionation coupled with multi-angle light scattering.

Electrical asymmetrical flow field-flow fractionation coupled with MALS was used to characterize the NIST monoclonal antibody reference material 8671.

This application note presents the characterization of ribosomal RNA using asymmetrical flow field-flow fractionation coupled with multi-angle light scattering.

This study describes the characterization of metal-containing nanoparticles in tattoo ink using AF4 coupled with multi-angle light scattering and ICP-MS.

This study describes the characterization of metal-containing nanoparticles in tattoo ink using AF4 coupled with multi-angle light scattering and ICP-MS.

Avoid precipitation of concentrated samples by splitting the pump channels: organic phase will pass through the autosampler; aqueous phase will join at the column head.

Avoid precipitation of concentrated samples by splitting the pump channels: organic phase will pass through the autosampler; aqueous phase will join at the column head.

Download the Executive summary

Download the Q&A

This application note shows how to achieve higher recoveries for commercially available MAbs using 15 % isopropanol as modifier in HIC mode.

μPAC™ technology has been used for analysing HCP impurities originating from recombinant expression systems used in the production of mAb based biotherapeutics.

The landscape for new biological drug development continues to evolve in complexity. With biosimilars entering the market and originator products coming off patent, the competitive race for market dominance is reliant on!

The landscape for new biological drug development continues to evolve in complexity. With biosimilars entering the market and originator products coming off patent, the competitive race for market dominance is reliant on!

In this application we show how to achieve the best separation and sensitivity for insulin UHPLC-MS analysis by using formic acid as a weak ion pairing agent.