Gas Chromatography (GC)

In a note recently published in Clincal Chemistry, researchers describe a method for detection of N2O in exhaled air by using gas chromatography (GC).

Triclosan is an ubiquitous antibacterial, antimicrobial chemical found in numerous consumer health care products today. This article demonstrates that triclosan can be quantitatively determined in commercial hand soaps using reversed-phase solid-phase disk extraction coupled to quantification using capillary gas chromatography-atomic emission detection while avoiding emulsions.

This article presents modified GC-MS method for the analysis of volatile organic compounds by method 8260; this method will dramatically increase instrumental throughput.

Phenomenex, Inc., a global leader in the separation sciences business, has been notified by R&D Magazine that it has won the coveted R&D 100 Award for the second year in a row.

The exact method used depends upon the type of hydrocarbon contamination in the soil.

The volatile extraction market consists of three techniques: purge and trap, headspace, and thermal desorption equipment. These systems are often employed as a sampling method for gas chromatography (GC) instrumentation but are also used with IR detectors, electrochemical sensors of electronic noses, and mass spectrometers.

The laboratory life science and analytical instrument industry is comprised of a large, diverse group of organizations that manufacture and distribute their products worldwide. However, overall industry sales are concentrated among a small set of companies. Approximately 950 firms are included in the industry, but only about 100 companies have sales above $50 million.

In this month's issue, columnist Ron Majors and coauthors discuss the important steps in the successful production of fused-silica gas chromatography (GC) capillary columns.

Optimizing peak shape in capillary gas chromatography (GC) is essential for the consistent, accurate analysis of residual solvents in pharmaceutical compounds.

According to an Agilent Technologies publication on sports drug testing (1), the first screening step (with a urine sample, for example) typically is performed using gas chromatography (GC).

Peptide mapping is one of the preferred techniques for the comprehensive characterization of biopharmaceutical products and is often the analytical method of choice for studying a protein's primary structure.

I started writing for LCGC in the summer of 1987. At the time, I was involved with an instrument company team specifying a new gas chromatograph.

The 58th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy was held February 25 to March 1, 2007, at McCormick Place in Chicago, Illinois.

In the half-century since its introduction, gas chromatography (GC) has evolved into one of the most widely used tools for chemical analysis.

The complexity of the systems that are used vary from standard GC configurations to assess the effectiveness of protective clothing to trace analysis of biomedical samples with complex GC configuration.

Negative chemical ionization GC-MS, used in conjunction with automated cold-on-column injection, provides efficient and sensitive quantification of explosive residues for environmental and forensic applications.

Chiral technology has become a very important aspect for scientists involved in the pharmaceutical, chemical, and agricultural industry.

The continual increase in sample numbers in busy labs means that it is often difficult for quality control or contract analysis labs to maintain short turnaround times, particularly when instruments are already running at full capacity. To address the need for faster analysis while retaining the quality of separation offered by dedicated amino acid analysers, an improved formulation of sodium citrate based buffers has been developed by Biochrom.

It may be somewhat audacious to claim that some methods in GCÃ-GC can be called non-classical - the technique has only been around for about 15 years and one might argue that this is not long enough to establish a suite of classical methods.

The accuracy and precision of results in gas chromatography and other analytical techniques are highly dependent upon the sample and its preparation, the instrumentation, accessories and operating conditions, as well as operator skill and experience. For these reasons, accuracy and precision for a specific methodology can be expected to vary from one laboratory or operator to another. This month, we look at statistical analysis as a diagnostic tool.

Setting realistic expectations requires a good working knowledge of an instrument's capabilities in terms of the sample requirements as well as an understanding of the effects of real-world samples and their matrices on long-term instrument performance.

Separation instrument techniques are among the most widely used technologies in the analytical instrumentation market. They span the entire industrial and regional marketplace. The lab separations market includes chromatographic techniques such as analytical and preparative HPLC, GC, IC, TLC, flash, and low pressure LC.

Research group: Professor Jan Andersson, Institute of Inorganic and Analytical Chemistry, University of Münster, Münster.

in this month's "GC Connectios," John Hinshaw continues a discussion of accuracy and precision begun in an earlier installment.