Gas Chromatography (GC)

What critical components can help to resolve the separation challenges related to pesticides analysis in food?

HRMS is widely used in chromatography for analyzing complex mixtures. However, chromatographers should take note of the exponentially larger data set that HRMS provides before deciding whether to use the technique for the analysis they are conducting.

We offer troubleshooting tips for various gas chromatography (GC) detectors, as well as provide an overview of the different options chromatographers have when using a GC detector.

A new approach based on post-column in situ hydrogenolysis, and flame ionization was used here to improve characterization of volatile aldehydes. We review and describe that approach here.

What can chiral capillary GC do for you? The answer lies in what analysis one is attempting to accomplish. Here, we discuss the utility of chiral capillary GC and where the technique is most valuable, focusing on three application areas in particular.

A chronological examination of GC is presented here, with a look at where the technique is heading and how it can be used to advance environmental sustainability.

Giorgia Purcaro of the University of Liège discusses the advantages offered by the liquid chromatography–comprehensive multidimensional gas chromatography time-of-flight mass spectrometer/flame ionization detector (LC–GCxGC–TOF-MS/FID) method in the analysis of mineral oil.

This instalment explores the challenges involved in detecting the effluent from a capillary gas chromatographic column and summarizes the many detector options.

An overview of different approaches for the qualitative and quantitative analysis of polysorbates.

Understanding separation principles is the key to success. Here's why.

Sauce-flavor or sauce-aroma baijiu, one variant of a popular Chinese liquor, is treated with a fermentation starter called daqu, giving the concoction a unique taste profile, and scientists want more information about how it can inform the manufacturing of higher-quality baijiu.

Among the compounds of concern found in the samples were nicotine-related alkaloids, psychoactive cannabinoids, and chemicals that promoted inflammation of the respiratory system.

While both branched-chain fatty acids (BCFAs) and straight-chain fatty acids (SCFAs) were analyzed, the profiling of BCFAs was considered especially important for future metabolomics and lipidomics studies.

Photoionization detectors (PIDs) are attractive for their high sensitivity and fast response time, while cost-effective equipment has been sought for online monitoring of volatile organic compounds (VOCs).

A research team has investigated the impact of hydrophilic/lipophilic balance (HLB) on the porogenic properties of non-ionic surfactants for chromatographic separation.

Quality control of raw hazelnuts is already a highly specific process, but has limitations including operator influence, duration, and lack of standardization. AI is now assisting in quality decision-making using GC×GC analysis.

Researchers have recalibrated polyparameter linear free energy relationships (PP-LFERs) for low-density polyethylene (LDPE) passive samplers. By utilizing a robust regression method and reliable partition coefficients and solute descriptors, the recalibrated models exhibited improved predictive performance, accurately estimating LDPE-water and LDPE-air partition coefficients across a wide range of compounds.

Stephanie Rankin-Turner and colleagues at Johns Hopkins Bloomberg School of Public Health have recently performed research in Zambia indicating that mosquitoes are more attracted to humans who exhibit abundant levels of certain volatile carboxylic acids.

While most diapers do not contain all 15 polycyclic aromatic hydrocarbons (PAHs), the concentration of these compounds varies by manufacturer, and no disposable diaper is entirely free of PAHs.

The combination of deep eutectic solvents (DESs) and cellulose paper, according to the researchers, bridges a current gap in sustainable, paper-based sorptive phases.

Nitrated polycyclic aromatic hydrocarbons (nitro-PAHs) are suspected to be carcinogenic, and improvements are sought to improve gas chromatography–mass spectrometry (GC–MS) methods traditionally used for this analysis.

Researchers compare the separation efficiency of olefins and paraffins using stationary phases containing silver(I) ions in ionic liquid (IL) and polymeric ionic liquid (PIL) matrices for gas chromatography techniques.

Researchers have introduced a novel primary method utilizing gas chromatography–isotope dilution infrared spectrometry (GC–IDIR) for accurate peptide purity analysis.

A novel isotopologue was synthesized in a stable isotope dilution assay (SIDA) for quantification of γ-nonalactone for the first time in pinot noir wines from New Zealand.

Enhancements in chromatographic performance were reviewed as were experimental concerns, both pointing toward using specific solvents to influence more sustainable industrial development.

Scientists have developed a novel sorbent, diphenyl-functionalized nickel foam (NF-2Ph), for the accurate detection of polycyclic aromatic hydrocarbon (PAH) contaminants in Chinese herbal medicines. The method, which combines dispersive solid-phase extraction (DSPE) with gas chromatography-mass spectrometry (GC–MS) analysis, offers high sensitivity and precision, providing a reliable approach for quality control and safety assessment of these medicinal products.

Pop quiz – can you define resolution? Would you be surprised at the number of correct answers? Which one is the best for chromatographers? In this LCGC Blog, we look at the various ways resolution can be interpreted scientifically.

Gas chromatography coupled to mass spectrometry (GC–MS) has been the gold standard in this application, but its limitations in differentiating cancer subtypes have led to the exploration of newer related technologies.

A recent study reveals that pesticide residues in herbs have a low transfer rate to herbal infusions, ensuring safer consumption of these products. The validated analytical method used in the study provides valuable insights into the levels of pesticide residues in herbs and their limited presence in the resulting infusions.

Webinar Date/Time: Tuesday, July 11, 2023 at 11am EDT | 8am PDT | 10am CEST