Gas Chromatography (GC)

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Nicholas H. Snow

Gas chromatography is a premier technique for quantitative analysis. As gas chromatographs have become simpler to use and data systems more powerful, much of the data processing involved in delivering quantitative results now happens in the background and is seemingly invisible to the user. In this installment, we will review the calibration techniques used with gas chromatography. We will compare calibration methods and the assumptions that underlie them. We will explore common mistakes and challenges in developing quantitative methods and conclude with recommendations for appropriate calibration methods for quantitative problems.

Town Hall in center of Leuven at sunset, Belgium | Image Credit: © Mistervlad - stock.adobe.com

HTC-18 Preview

The 18th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-18) will be held from 28–31 May 2024 in Leuven, Belgium.

Leandro Wang Hantao is an assistant professor at the Institute of Chemistry at the University of Campinas in Brazil. His research group is dedicated to developing fundamental and applied research in all aspects of conventional and multidimensional gas chromatography, with a particular emphasis on chemometrics. His work has been recognized with awards, including the prestigious “John B. Phillips Award” in 2019.

LCGC spoke to Leandro Wang Hantao from the University of Campinas in São Paulo, Brazil, about his work investigating the influence of ion management parameters on the data produced by comprehensive gas chromatography–high-resolution mass spectrometry (GC×GC–HRMS) equipped with a fourier transform-orbital ion trap mass analyzer, and his investigation into employing channel occlusion for sample preparation in untargeted analysis in petroleomics.