Gas Chromatography (GC)

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Top view of vials are arranged in the auto sampler for GC chromatography in laboratory with microscope testing background | Image Credit: © Anchalee - stock.adobe.com.

In this installment, we examine several of the common parameters that can affect automated peak integration and the resulting peak areas. We will consider how the data system detects the beginning and end of the peak, how it determines the peak maximum, how real peaks are differentiated from noise, and how signals at individual time intervals are summed to generate the peak area.

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On February 25, a Pittcon oral session, titled “Detection of PFAS and other Polyfluorinated Analytes,” took place at the San Diego Convention Center in San Diego, California. This session included six talks that covered a variety of analytical techniques currently being used in per- and polyfluoralkyl (PFAS) analysis.

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The 18th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology will take place from 28–31 May 2024 in Leuven, Belgium.

Nicholas H. Snow

Gas chromatography is a premier technique for quantitative analysis. As gas chromatographs have become simpler to use and data systems more powerful, much of the data processing involved in delivering quantitative results now happens in the background and is seemingly invisible to the user. In this installment, we will review the calibration techniques used with gas chromatography. We will compare calibration methods and the assumptions that underlie them. We will explore common mistakes and challenges in developing quantitative methods and conclude with recommendations for appropriate calibration methods for quantitative problems.

Town Hall in center of Leuven at sunset, Belgium | Image Credit: © Mistervlad - stock.adobe.com

HTC-18 Preview

The 18th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-18) will be held from 28–31 May 2024 in Leuven, Belgium.