November 5th 2024
Informative panel discussions featuring key opinion leaders from the separation science sector discussing the latest technology trends and developments in liquid chromatography, gas chromatography, sample preparation, and data handling.
GC–MS Analysis of PFAS Expands Knowledge of Toxicokinetic Data
March 29th 2024A study has proposed targeted methods, developed using gas chromatography coupled to tandem mass spectrometry, to measure human plasma protein binding and hepatocyte clearance in 73 per- and polyfluoroalkyl substances, or PFAS.
Inside the Laboratory: The Gionfriddo Group at the University at Buffalo
March 28th 2024In this edition of “Inside the Laboratory,” Emanuela Gionfriddo, PhD, an associate professor of chemistry at the University at Buffalo, discusses her group’s current research endeavors, including using solid-phase microextraction (SPME) coupled to liquid chromatography (LC) and gas chromatography (GC) to further understand the chemical relationship between environmental exposure and disease and elucidate micropollutants fate in the environment and biological systems.
Inside the Laboratory: The Schug Group at the University of Texas at Arlington
March 22nd 2024In this edition of “Inside the Laboratory,” Kevin Schug, PhD, a full professor of chemistry at the University of Texas at Arlington, discusses his laboratory’s group work in environmental monitoring around water and soil quality near oil and gas extraction, using techniques such as liquid chromatography (LC), gas chromatography (GC), supercritical fluid chromatography (SFC), and coupling these techniques with mass spectrometry (MS).
Profiling VOCs in Whisky with GC×GC–MS
March 6th 2024Researchers from Austria, Greece, and Italy conducted a study to analyze volatile organic compounds (VOCs) present in Irish and Scotch whiskys using solid-phase microextraction (SPME) Arrow with comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×GC–MS) to examine the organoleptic characteristics that influence the taste of spirits.
From Detector to Decision, Part IV: Demystifying Peak Integration
March 1st 2024In this installment, we examine several of the common parameters that can affect automated peak integration and the resulting peak areas. We will consider how the data system detects the beginning and end of the peak, how it determines the peak maximum, how real peaks are differentiated from noise, and how signals at individual time intervals are summed to generate the peak area.
Pittcon 2024: Identifying PFAS in Anti-Fog Products Using GC-TOFMS
February 25th 2024During a workshop at Pittcon, David Alonso of LECO Corporation discussed how gas chromatography–time-of-flight mass spectrometry (GC-TOFMS) can be used to identify polyfluorinated alkyl chemicals (PFAS) chemicals in anti-fog product solutions.
Pittcon 2024: Chromatographic Techniques Used to Detect PFAS
February 25th 2024On February 25, a Pittcon oral session, titled “Detection of PFAS and other Polyfluorinated Analytes,” took place at the San Diego Convention Center in San Diego, California. This session included six talks that covered a variety of analytical techniques currently being used in per- and polyfluoralkyl (PFAS) analysis.
Comprehensive Analysis Unveils Chemical Composition of Lingbao Huxin Dan for Cardiovascular Health
February 7th 2024Researchers employed advanced chromatography and mass spectrometry techniques to unravel the chemical components and metabolites of Lingbao Huxin Dan, pinpointing its therapeutic potential for cardiovascular ailments.
Study Enhances Crop Yield by Precisely Identifying High-Quality Seeds
February 1st 2024Distinguishing between viable and non-viable seeds requires an advanced chromatographic technique. A study conducted by researchers from China Agricultural University highlights how HS-GC-IMS can be used to help solve this frequent problem in the agricultural industry.
Evaluating Consistency in Inverse Gas Chromatography: Insights from an Interlaboratory Study
January 1st 2024Researchers from Europe conducted the first known interlaboratory study on inverse gas chromatography (IGC), revealing significant variations in dispersive surface energy values and retention volumes for standard materials.
From Detector to Decision, Part III: Fundamentals of Calibration in Gas Chromatography
January 1st 2024Gas chromatography is a premier technique for quantitative analysis. As gas chromatographs have become simpler to use and data systems more powerful, much of the data processing involved in delivering quantitative results now happens in the background and is seemingly invisible to the user. In this installment, we will review the calibration techniques used with gas chromatography. We will compare calibration methods and the assumptions that underlie them. We will explore common mistakes and challenges in developing quantitative methods and conclude with recommendations for appropriate calibration methods for quantitative problems.