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For GC, how do data systems both assist and hinder us in obtaining maximum information from chromatograms? We explain how a chromatogram can provide a wealth of information about an individual analyte in a sample, about the sample itself, and about how well a GC instrument is performing.

What Chromatograms Can Teach Us About Our Analytes

Tony Taylor is Group Technical Director of Crawford Scientific Group and CHROMacademy. His background is in pharmaceutical R&D and polymer chemistry, but he has spent the past 20 years in training and consulting, working with Crawford Scientific Group clients to ensure they attain the very best analytical science possible. He has trained and consulted with thousands of analytical chemists globally and is passionate about professional development in separation science, developing CHROMacademy as a means to provide high-quality online education to analytical chemists. His current research interests include HPLC column selectivity codification, advanced automated sample preparation, and LCâMS and GCâMS for materials characterization, especially in the field of extractables and leachables analysis.

Judicious initial choices of gas chromatography (GC) column dimensions, and even a change of column dimension during method development, can lead to significant improvements in resolution.

An Excerpt from "Optimizing Gas Chromatography Using Column Dimensions"

As we approach the holiday season, in what has a been the most challenging of years both inside and outside of the laboratory, I wanted to produce a more light-hearted yet inspiring review of 2020 within the Arch Sciences Group laboratories.

The LCGC Blog: 12 Tips for a Chromatography Christmas

Rola Elabaji is the Product Marketing Manager for gas and flash chromatography at Phenomenex. Rola has a Project Management Certificate (PM) from UCLA, a Master’s in Chemistry from the Lebanese University (LU) Faculty of Science, Lebanon, and an Experimental Science Baccalaureate from Elite College, Lebanon. She has over 10 years’ experience in chromatography products and processes. Prior to Marketing, Rola began her career at Phenomenex in 2004 as a Quality Control Specialist, then joining the Manufacturing Engineering Technology department as a Team Project Coordinator in 2006.


How can GC overcome the complexity of dioxin separation and analysis?

Advances in Gas Chromatography  for Optimal Dioxin  GC Separation

This instalment explores how the data system controls the functions of the GC instrument. Drawing on classical electronics and instrument designs, the article describes the evolution of instrument controls from knobs and gauges on the front panel of the instrument to computer control and current web-based systems.

Control or Chaos: How Can We Run a Gas Chromatograph from Anywhere?

Computers control all aspects of modern GC instrument operation, from temperature to valve actuation. We look under the hood to see how this works.

How Can We Run a Gas Chromatograph from Anywhere?

Capillary GC is renowned for being a ”high efficiency” technique, meaning that we typically see very narrow peaks within our chromatograms. This leads to the ability to separate many components in a reasonable amount of time, which is of course analytically advantageous.

The LCGC Blog: Troubleshooting Gas Chromatography Part V – Loss of Efficiency (and Resolution!)

Barbara Giocastro is currently a Ph.D. student in chemical sciences at the University of Messina.

Ivan Aloisi is currently a Ph.D. student in chemical sciences at the University of Messina.

In the present research, similar chromatography fingerprints were obtained using finely-tuned cryogenic-modulation (CM) and flow-modulation (FM) comprehensive two-dimensional gas chromatography–mass spectrometry (GC×GC–MS) experimental conditions.

Cryogenic- and Flow-Modulation Comprehensive Two-Dimensional Gas Chromatography–Mass Spectrometry: Obtaining Similar Chromatography Performances

Using the flame ionization detector (FID) as an example, we explain how the detector in a GC system generates a signal and how it is processed into chromatograms, and explore modern aspects of storing and processing digital data.

From Detector to Decision: How Does the GC Instrument Generate Your Data? 

In gas chromatography, heating the sample in the inlet can lead to sample losses and loss of quantitative reproducibility, but these problems can be avoided using cold sample introduction. This article describes various types of cold injection and how they can benefit the analyst.

Gas Chromatography (GC) | Topics