LC–MS

The researchers explored ways to simplify retention time calculation across LC–MS and various other chromatographic methods.

This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.

A new method has been created for determining N-nitrosamines (NAs) in pharmaceutical preparations using liquid chromatography with tandem mass spectrometry.

A new approach to characterizing human milk oligosaccharides was developed using a combination of liquid chromatography, mass spectrometry, and other techniques.

New types of smart proteolytic samplers were tested for their effectiveness in liquid chromatography-mass spectrometry (LC–MS)-based protein quantification.

Webinar Date/Time: Wed, Apr 16, 2025 11:00 AM EDT

Scientists from the Zhejiang Institute of Quality Scientists used liquid chromatography–tandem mass spectrometry to detect 35 PFAS in paper and plastic products.

Webinar Date/Time: Wed, Apr 9, 2025 10:00 AM EDT

Webinar Date/Time: Wed, May 21, 2025 11:00 AM EDT

Nadia Gadi and Allisson Barros de Souza spoke to LCGC International about their investigation into the application of electrochemical advanced oxidation processes (eAOPs) for the efficient removal of pharmaceutical residues in wastewater.

Webinar Date/Time: Thursday, April 17, 2025 8am PST | 11am EST | 4pm GMT | 5pm CET

During Waters Corporation’s 2025 Investor Day, the company’s top executives highlighted the company’s growth and hints at future points of development.

Here is some of the most popular content posted on LCGC International this week.

Webinar Date/Time: Thurs, March 27, 2025 11:00 AM EST

Here is some of the most popular content posted on LCGC International this week.

Here is some of the most popular content posted on LCGC International this week.

Ardiana Kajtazi discusses her research identifying organic micropollutants in water using liquid chromatography–high-resolution mass spectrometry (LC–HRMS). She highlights the standardized filtration approach her team has developed based on intersection principles, utilizing retention indices from two reversed-phase liquid chromatography (RPLC) columns.

The Harvey W. Wiley Award is presented every year to a scientist, or group of scientists, who have made outstanding contributions to analytical method development in areas of interest to AOAC INTERNATIONAL.

A team of researchers has evaluated approaches in exposome research, highlighting sample preparation, MS-based platforms, and data acquisition strategies.

A QuEChERS sample preparation technique coupled with a UHPLC–MS/MS method was developed to determine 19 veterinary drug residues in foods of animal origin.

ACD/Labs recently released their 2025 Structure Elucidation & Verification Report, discussing how informatics trends have shifted since 2022.

A list of the Top 10 LCGC Articles of the Month: Highlighting Diverse Topics in Separation Science

A new method has been created for determining N-nitrosamines (NAs) in pharmaceutical preparations using liquid chromatography with tandem mass spectrometry.

University of Turin scientists developed a UHPLC–PDA-MS/MS-based method for quantifying plant-specialized metabolites for determining the quality of medicinal and aromatic plants.