
This article will discuss an ion-pair reversed-phase liquid chromatography mass spectrometry (IP-RPLC–MS) workflow for the characterization of three messenger RNA (mRNA) key critical quality attributes: 5’ Cap, ORF, and poly(A) tail.

In this edition of “Inside the Laboratory,” Susan Richardson of the University of South Carolina discusses her laboratory’s work with using electron ionization and chemical ionization with gas chromatography–mass spectrometry (GC–MS) to detect DBPs in complex environmental matrices, and how her work advances environmental analysis.

This article will discuss an ion-pair reversed-phase liquid chromatography mass spectrometry (IP-RPLC–MS) workflow for the characterization of three messenger RNA (mRNA) key critical quality attributes: 5’ Cap, ORF, and poly(A) tail.

Here is some of the most popular content posted on LCGC International this week.

Peng Che fom Vrije Universiteit Amsterdam in the Netherlands discusses the benefits of hyphenating liquid chromatography (LC) with electron activated dissociation mass spectrometry (EAD-MS) to analyze cathinone positional isomers.

Mithibai College of Arts scientists recently used liquid chromatography-tandem mass spectrometry (LC–MS/MS) for detecting nitrosamines in blood pressure medication.

Scientists recently developed new GC/LC-Q-TOF/MS-based method for determining pesticides in Angelica sinensis, a traditional Chinese medicine.

LCGC International sat down with Faith Johnson of ECOLAB to discuss her career and work with the Females in Mass Spectrometry (FeMS) group.

A study has used gas chromatography coupled to a time-of-flight mass spectrometer to build an electron ionization mass spectra database of more than 250 chemicals classified as either volatile or semi-volatile compounds. An additional, confirmatory layer of liquid chromatography–mass spectrometry analysis was subsequently performed.

The evolution of LC–MS for characterizing mRNA therapeutics is discussed.

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Webinar Date/Time: Mon, Nov 18, 2024 11:00 AM EST

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Webinar Date/Time: Thu, Nov 14, 2024 10:00 AM EST

Here is some of the most popular content posted on LCGC International this week.

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Webinar Date/Time: Wednesday, November 13, 2024 Airing 1: 11am EDT | 8am PDT | 4pm BST | 5pm CEST Airing 2: 2pm EDT | 11am PDT | 7pm BST | 8pm CEST

Biotech Fluidics recently released the Biotech Micro Flow Meter, a tool for continuously monitoring the consistency of nanoscale dispensing systems as well as UHPLC and LC/MS solvent/reagent delivery systems.

Scientists from the Institute of Analytical Chemistry of the Czech Academy of Sciences and Masaryk University recently tested various saliva sampling methods to optimize bile acid analysis.

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Webinar Date/Time: Thu, Nov 7, 2024 11:00 AM EDT

This review aims to provide a summary of the most current analytical techniques and their applications in per- and polyfluoroalkyl substances (PFAS) research, contributing to the ongoing efforts to monitor and mitigate PFAS contamination.

Raquel Gonzalez de Vega of the University of Graz recently spoke to us about her work tracking per- and polyfluoroalkyl substances (PFAS) in ski wax products.

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Webinar Date/Time: Tue, Nov 12, 2024 11:00 AM EST

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Webinar Date/Time: Fri, Nov 8, 2024 11:00 AM EST

The European Commission's regulation on maximum levels for certain contaminants in food highlights the need for precise and reliable methods to quantify per- and polyfluoroalkyl substances (PFAS) in various food matrices. This article discusses development and validation of a robust method for analyzing 21 PFAS compounds in chicken eggs using solid-phase extraction (SPE) and liquid chromatography–mass spectrometry (LC–MS).

As part of our ISC 2024 coverage, we recently interviewed Anneli Kruve of Stockholm University about her scientific background and her presentation about eludicating toxic chemicals' structures using LC/HRMS.

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Webinar Date/Time: Thu, Nov 7, 2024 9:00 AM PST (12:00 PM EST)

As part of our ISC 2024 coverage, we recently interviewed Alexandre Goyon of Genentech about his research and his being awarded our Rising Stars of Separation Science Award for Outstanding Achievement in Pharmaceutical Analysis.

As part of our ISC 2024 coverage, we recently interviewed Amarande Murisier of the University Hospital of Lausanne, Switzerland (CHUV) about her winning the Rising Stars of Separation Science Award for Biopharmaceutcal Analysis and her scientific background.

Here is some of the most popular content posted on LCGC International this week.