LC–MS

High-performance liquid chromatography (HPLC) was recently used to detect acylated impurities in artificial hormones meant to treat prostate cancer symptoms.

Chinese researchers created a new approach for identifying and quantifying illegal additives in fruit and vegetable plums, types of often-consumed health-care foods.

Here is some of the most popular content posted on LCGC International this week.

Webinar Date/Time: Wednesday, May 28, and Thursday, May 29, 2025 Morning Sessions: 2:00pm BST | 9:00am EST | 3:00pm CEST Lunchtime Sessions: 5:30pm BST | 12:30pm EST | 6:30pm CEST Afternoon Sessions: 6:30pm BST | 1:30pm EST | 7:30pm CEST

Webinar Date/Time: Thu, May 22, 2025 11:00 AM EDT

This new study presents a validated QuEChERS–LC-MS/MS method for detecting eight persistent, mobile, and toxic substances in escarole, tomatoes, and tomato leaves irrigated with contaminated water.

This study highlights the promising potential of LC–MS as a powerful tool for mAb quality control within the context of upstream processing.

Haloacetic acid detection has become important when analyzing drinking and swimming pool water. University of Tasmania researchers have begun applying capillary liquid chromatography as a means of detecting these substances.

When analyzing samples using liquid chromatography–high-resolution mass spectrometry, there are various ways the processes can be improved. Researchers created new methods for prioritizing these strategies.

Here is some of the most popular content posted on LCGC International this week.

Two-dimensional liquid chromatography (2D-LC) coupled to mass spectrometry (MS) has been used to separate proteins in the venom of the Indian cobra snake.

Ping Wei powder is a type of traditional Chinese medicine used to treat digestive system diseases. Its growth in popularity has led to scientists seeking to properly identify its chemical profile.

Novichok nerve agents are lethal substances when improperly handled. The researchers from the University of Helsinki aimed to find new ways of neutralizing Novichok A-234.

Webinar Date/Time: Tue, May 13, 2025 11:00 AM EDT

Flavonoids are widely used metabolites that carry out various functions in different industries, such as food and cosmetics. Detecting, separating, and quantifying them in fruit species can be a complicated process.

Here is some of the most popular content posted on LCGC International this week.

Texas Tech University researchers used liquid chromatography–tandem mass spectrometry to quantify glucose transporter 1 (GLUT1) in mammalian brain cells.

Karolinska University Hospital researchers recently tested new approaches for analyzing drugs of abuse in oral fluids.

A recent roundtable discussion featuring Aloka Srinivasan of Raaha, Mayank Bhanti of the United States Pharmacopeia (USP), and Amber Burch of Purisys discussed the challenges surrounding nitrosamine analysis in pharmaceuticals.

Webinar Date/Time: Tuesday, May 20, 2025 Session 1: 10am CET | 4pm SGT | 4am ET Session 2: 3pm CET | 9pm SGT | 9am ET

Here is some of the most popular content posted on LCGC International this week.

During a recent LCGC International peer exchange discussion on nitrosamine analysis, our professional panelists discussed the complex issues surrounding the processes for detecting nitrosamines.

A multidimensional liquid chromatography (LC)-based technique was created to help profile antioxidant metabolites in onion leaf extracts.

David Megson from Manchester Metropolitan University in Manchester, UK, spoke to LCGC International about the latest developments in non-targeted analysis (NTA) of per- and polyfluoroalkyl substances (PFAS) in environmental matrices based on a recent systematic review paper he has collaboratively published (1).

Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.