LC–MS

Ping Wei powder is a type of traditional Chinese medicine used to treat digestive system diseases. Its growth in popularity has led to scientists seeking to properly identify its chemical profile.

Novichok nerve agents are lethal substances when improperly handled. The researchers from the University of Helsinki aimed to find new ways of neutralizing Novichok A-234.

Webinar Date/Time: Tue, May 13, 2025 11:00 AM EDT

Flavonoids are widely used metabolites that carry out various functions in different industries, such as food and cosmetics. Detecting, separating, and quantifying them in fruit species can be a complicated process.

Here is some of the most popular content posted on LCGC International this week.

Texas Tech University researchers used liquid chromatography–tandem mass spectrometry to quantify glucose transporter 1 (GLUT1) in mammalian brain cells.

Karolinska University Hospital researchers recently tested new approaches for analyzing drugs of abuse in oral fluids.

A recent roundtable discussion featuring Aloka Srinivasan of Raaha, Mayank Bhanti of the United States Pharmacopeia (USP), and Amber Burch of Purisys discussed the challenges surrounding nitrosamine analysis in pharmaceuticals.

Webinar Date/Time: Tuesday, May 20, 2025 Session 1: 10am CET | 4pm SGT | 4am ET Session 2: 3pm CET | 9pm SGT | 9am ET

Here is some of the most popular content posted on LCGC International this week.

During a recent LCGC International peer exchange discussion on nitrosamine analysis, our professional panelists discussed the complex issues surrounding the processes for detecting nitrosamines.

A multidimensional liquid chromatography (LC)-based technique was created to help profile antioxidant metabolites in onion leaf extracts.

David Megson from Manchester Metropolitan University in Manchester, UK, spoke to LCGC International about the latest developments in non-targeted analysis (NTA) of per- and polyfluoroalkyl substances (PFAS) in environmental matrices based on a recent systematic review paper he has collaboratively published (1).

Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.

In this final part of our interview with Females in Mass Spectrometry (FeMS) Empowerment Award Winner Josephine Ouma, we discuss her future research efforts and what Women's History Month means to her.

In this second part of our interview with Females in Mass Spectrometry (FeMS) Empowerment Award Winner Josephine Ouma, we discuss her experience with mass spectrometry and how FeMS has impacted her life.

In this first part of our interview with Females in Mass Spectrometry (FeMS) Empowerment Award Winner Josephine Ouma, we discuss her PhD research and what inspired her to join FeMS.

The researchers explored ways to simplify retention time calculation across LC–MS and various other chromatographic methods.

This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.

A new method has been created for determining N-nitrosamines (NAs) in pharmaceutical preparations using liquid chromatography with tandem mass spectrometry.

A new approach to characterizing human milk oligosaccharides was developed using a combination of liquid chromatography, mass spectrometry, and other techniques.

New types of smart proteolytic samplers were tested for their effectiveness in liquid chromatography-mass spectrometry (LC–MS)-based protein quantification.

Webinar Date/Time: Wed, Apr 16, 2025 11:00 AM EDT

Scientists from the Zhejiang Institute of Quality Scientists used liquid chromatography–tandem mass spectrometry to detect 35 PFAS in paper and plastic products.

Webinar Date/Time: Wed, Apr 9, 2025 10:00 AM EDT