LC–MS

Scientists from Hangzhou Medical College recently recorded the effectiveness of novel quality control strategies for the determination of vitamin D using liquid chromatography–tandem mass spectrometry (LC–MS/MS).

HRIM-MS has shown unique capabilities when used to analyze cyclic peptide therapeutics, and enhances the analysis of biopharmaceuticals by efficiently filtering out interfering compounds for direct analysis within a complex mixture. These findings demonstrate the technique's utility and versatility.

Scientists from China Pharmaceutical University developed a liquid chromatography-tandem mass spectrometry (LC–MS/MS)-based method for determining the presence of anti-colorectal cancer drugs in human plasma.

Webinar Date/Time: Session 1: Thursday, May 16, 2024 at 11am EDT | 8am PDT Session 2: Thursday, May 16, 2024 at 2pm EDT | 11am PDT Session 3: Thursday, May 16, 2024 at 11am AEST | 6pm PDT

Webinar Date/Time: Tuesday, May 28, 2024 Airing 1: 11am EDT | 8am PDT | 10am CET | 4pm SGT Airing 2: 2pm EDT | 11am PDT | 1pm CET | 7pm SGT

Scientists from the Chinese Academy of Inspection and Quarantine recently published a review on how green solvents can further the evolution of microextraction techniques.

Here are the top five articles that the editors of LCGC International published this week.

Scientists from the University of Córdoba in Córdoba, Spain recently used liquid chromatography–tandem mass spectrometry (LC–MS/MS) to comprehensively profile human ceramides to determine their reactions to diseases.

A recent study used ultrahigh-pressure liquid chromatography (UHPLC) to identify traces of drugs on smartphones.

Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.

Webinar Date/Time: Wed, May 15, 2024 2:00 PM EDT

Webinar Date/Time: Thu, May 23, 2024 1:00 PM EDT

The serum/plasma estradiol is useful for diagnosis, pathology, and therapeutic efficacy monitoring of estrogen-dependent diseases, according to the authors.

Scientists from Anhui University of Chinese Medicine in Hefei, China recently investigated the mechanisms behind what makes huachansu tablets, a type of traditional Chinese medicine (TCM), effective against liver cancer.

On the occasion of Earth Day, University of Wisconsin-Madison graduate student and chemist Katelyn Michael speaks with LCGC about the methods she has been using to attempt to degrade known PFAS.

Here are the top five articles that the editors of LCGC International published this week.

Webinar Date/Time: Tue, May 21, 2024 11:00 AM EDT

Webinar Date/Time: Wed, Jun 5, 2024 11:00 AM EDT

Scientists from the Netherlands created a new LC–MS/MS assay to test new small molecular inhibitors (SMIs) and their effectiveness in prognosing lung cancer.

Chromatographic and spectroscopic techniques alike were reviewed for their current effectiveness and future potential in this lecture session at Analytica 2024.

The discovery of a novel lipid not yet seen in plants was found in four herbal teas using multivariate principal component analysis.

In this interview, Kevin Schug discusses his work using untargeted analysis and differentiation of psilocybin mushroom strains.

The 26th Norwegian Symposium on Chromatography was held 21–23 January 2024. The symposium has strong traditions in the Norwegian separation science community, serving as a forum for excellent scientific talks, networking, and social events.

A study has used gas chromatography coupled to a time-of-flight mass spectrometer to build an electron ionization mass spectra database of more than 250 chemicals classified as either volatile or semi-volatile compounds. An additional, confirmatory layer of liquid chromatography–mass spectrometry analysis was subsequently performed.

Scientists recently tested a new system for detecting and extracting favipiravir from plasma samples.

Scientists from the Affiliated Hospital of Putian University recently analyzed the dysregulation of lipid metabolism in patients suffering from chronic hepatitis B patients.

This week, LCGC International published a variety of articles on the hottest topics in chromatography and beyond. Below, we’ve highlighted some of the most popular articles, according to our readers. Happy reading!

In this edition of “Inside the Laboratory,” Kevin Schug, PhD, a full professor of chemistry at the University of Texas at Arlington, discusses his laboratory’s group work in environmental monitoring around water and soil quality near oil and gas extraction, using techniques such as liquid chromatography (LC), gas chromatography (GC), supercritical fluid chromatography (SFC), and coupling these techniques with mass spectrometry (MS).

In a recent study from the GITAM School of Pharmacy, two scientists used different liquid chromatography techniques to assess the properties of ozenoxacin (OXC) and its degradation products.

In a recent review article, researchers from Concordia University examined recent advancements in LC–MS workflows for tissue lipidomics.