The Application Notebook
A highly sensitive analytical method for the analysis of tamsulosin in human plasma has been developed for use in bioanalytical studies. The solid-phase extraction (SPE) and UPLC–MS–MS methodologies are described, as well as performance against validation parameters.
LCGC North America
Columnist Ron Majors discusses some of the practical considerations in the successful application of the popular yet age-old technique of solvent extraction (also known as liquid–liquid extraction, or LLE).
Researchers from National Tsing Hua University (Hsinchu, Taiwan) developed a dispersive liquid?liquid microextraction (DLLME) method based on solidification of a floating organic drop and combined it with gas chromatography with either electron-capture or mass spectrometry detection.
A research group from the University of La Laguna and ICIA (both in La Laguna, Tenerife, Canary Islands, Spain) used multiwalled carbon nanotubes as a solid-phase extraction (SPE) medium for extracting eight organophosphorus pesticides from various commercial apple, grape, orange, and pineapple juices.
Researchers from the University of Barcelona (Barcelona, Spain) and Arboriculura Mediterranea Mas de Bover (Tarragona, Spain) implemented a factorial experimental design in developing a solid-phase microextraction (SPME)?gas chromatography (GC)?mass spectrometry (MS) method to analyze volatile phenols in virgin olive oils.
Scientists from Lanzhou University (Lanzhou, China) developed an automated on-line method for determining substituted aniline compounds that consisted of in-tube solid-phase microextraction (SPME) with oxidized multiwalled carbon nanotubes coated on the outside surface of the SPME fiber, which was inserted into PEEK tubing attached to a six-port injection valve.
Researchers from Hebei University and Baoding University (both in Baoding, China) used water-compatible molecularly imprinted polymers as a sorbent for solid-phase extraction (SPE) of nine quinolones from urine samples.
LCGC North America
An alphabetical listing of all 2008 LCGC articles by author and subject.
Tecan Group (Männedorf, Switzerland), a supplier of advanced automation and detection systems for life science laboratories, has opened its new Asia Pacific region headquarters in Shanghai, China.
Agilent Technologies (Santa Clara, California) and BioTrove (Woburn, Massachusetts) have signed a nonexclusive value-added reseller agreement that enables BioTrove to provide instrumentation for mass spectrometry?based drug discovery.
Spartan Bioscience Announces Agreement with NorDiag ASA
Malvern Instruments (Southborough, Massachusetts) announced its participation in the OPC Analyzer Device Integration Working Group.
Dionex (Sunnyvale, California) has agreed to purchase Caliper Life Sciences? (Hopkinton, Massachusetts) AutoTrace solid-phase extraction (SPE) products, including the AutoTrace SPE workstation, which is designed to automate the extraction of large-volume aqueous samples before analysis.
LCGC North America
This installment of SPP will compare and contrast the various types of polymeric and non-polymeric sorbents. The major advantages or polymeric sorbents will be discussed, and some applications will illustrate the versatility of polymeric SPE.
Researchers from the University of Córdoba (Córdoba, Spain) studied the use of simultaneous liquid-liquid microextraction and methylation along with headspace gas chromatography-mass spectrometry to determine nine haloacetic acids in drinking water.
A research group from Aristotle University of Thessaloniki (Thesaloniki, Greece) analyzed royal jelly, an important bee product, fortified with nine pesticides.
Researchers from US EPA National Exposure Research Laboratory (Research Triangle Park, North Carolina) and East Carolina University (Greenville, North Carolina) used supercritical fluid extraction (SFE) to recover aflatoxin B1 from fortified soil.
Chemists from the University of North Dakota (Grand Forks, North Dakota) used solid-phase microextraction (SPME) to extract aldehydes from an aqueous solution.
A research group from the University of Lisbon (Lisbon, Portugal) studied the use of stir-bar sorptive extraction (SBSE) with polyurethane and polydimethylsiloxane polymeric phases and high performance liquid chromatography with diode-array detection for the analysis of six acidic pharmaceutical compounds in environmental water matrices such as river, sea, and wastewater samples.
A research group from BRGM (Orleans, France) and Ecole Superieure de Physique et de Chimie Industrielles (Paris, France) used terbutylazine molecularly imprinted polymers following a pressurized liquid extraction step to remove interfering compounds from soil extracts containing the herbicide atrazine.
Researchers from Universidad Complutense de Madrid (Madrid, Spain) and Universität Dortmund (Dortmund, Germany) used a molecularly imprinted polymer (MIP) solid-phase extraction method in the analysis of fluoroquinolone antibiotics in environmental water samples.
Researchers from Hiroshima University (Hiroshima, Japan), Hiroshima Prefectural Police Headquarters (Hiroshima), Tokai University School of Medicine (Kanagawa, Japan), and GL Sciences Inc. (Saitama, Japan) developed a spin column device packed with octadecyl silane-bonded monolithic silica for extracting amphetamines and methylenedioxyamphetamines from urine.
Researchers from Universita degli Studi di Parma (Parma, Italy) used immunomagnetic beads to extract trace peanut allergen protein Ara h3/4 from breakfast cereals.
Scientists from Hoshi University (Tokyo, Japan) and the National Research Institute of Police Science (Chiba, Japan) employed stir-bar sorptive extraction (SBSE) and thermal desorption gas chromatography?mass spectrometry (GC?MS) for analyzing 5-chloro-2-(2,4-dichlorophenoxy)phenol, otherwise known as triclosan, in river water samples.
A research group from Yanbian University and the Key Laboratory of Organism Functional Factors of the Changbai Mountain (both Yanji City, Jilin Province, China) examined the effect of the vapor pressure of the extracting solvent on the enrichment factor in headspace liquid-phase microextraction.
