Sample Preparation

Incognito presents the first in a series on the pitfalls in the practice of modern SPE.

Ron Majors provides first-hand coverage of some of the technology and application advances reported at HPLC 2009.

The former "Milestones in Chromatography" editor returns to give readers the story of his time in the field.

Ron Majors discusses the technique of Salting-out Liquid-Liquid Extraction (SALLE) and provides some examples of its successful applications.

A method of sample preparation followed by reversed-phase high performance liquid chromatography (RP HPLC) with diode array (DA) detection.

Doug Kitson looks at some of Poland's leading separation science groups.

Researchers from Vertox Laboratory, Defence Research and Development Establishment (Gwalior, India) used a liquid-liquid-liquid microextraction technique followed by liquid chromatography?mass spectrometry (LC?MS) to examine alkyl alkylphosphonic acids, which are important environmental markers of nerve agents.

Researchers from Banyu Pharmaceutical Co. (Ibaraki, Japan) used a novel extraction method to prepare drugs in gelatin capsules for analysis by high performance liquid chromatography.

A research group from AlbaNova University Center, Royal Institute of Technology (Stockholm, Sweden) developed an automated method for purifying and desalting proteins before mass spectrometry analysis.

A research group from NRL Marine Biotoxins, Federal Institute for Risk Assessment (Berlin, Germany) developed a solid-phase extraction (SPE) method for the enrichment and clean-up of lipophilic marine biotoxins from various species of bivalve molluscs and processed shellfish products.

Scientists from Henan Normal University (Xinxiang, China) and the University of Science and Technology Beijing (Beijing, China) developed an ultrasound-assisted ionic liquid dispersive liquid-phase microextraction procedure for determining four aromatic amines in water samples.

Ron Majors provides an unbiased look at this present crisis and gives alternative solutions.

Thermo Fisher Scientific (Waltham, Massachusetts) has agreed to acquire Biolab, an Australian analytical instruments and life science consumables distributor, for $120 million (US).

Scientists from Brigham Young University (Provo, Utah) and US Synthetic Corporation (Orem, Utah) developed C18, C8, and perfluorinated diamond-based reversed-phase solid-phase extraction (SPE) media.

Researchers from the Research Institute for Chromatography (Kortrijk, Belgium) and AstraZeneca R&D Charnwood (Loughborough, UK) used in-situ derivatization and liquid chromatography?mass spectrometry (LC?MS) to analyze arylamines and aminopyridines, which can be present as potentially genotoxic impurities in pharmaceutical preparations at trace levels.

The ionic strength of a sample and the solvent used to dissolve it play a pivotal role in routine capillary electrophoresis (CE).

Researchers from Uppsala University (Uppsala, Sweden) added alkali salts to protein samples in preparation for capillary electrophoresis (CE) analysis of intact proteins.

The guest columnists review SBSE and HSSE and examine their advantages and limitations, along with providing approaches to overcoming the latter.

Researchers from the University of Thessaly (Volos, Greece) used a single-drop microextraction technique with gas chromatography (GC) and nitrogen?phosphorus and electron-capture detection to analyze pesticides in vegetables.

Scientists from Sezione di Tecnologie Alimetari (Firenze, Italy) and the University of California, Davis (Davis, California) analyzed grape aroma compounds in Cabernet Sauvignon grapes using headspace solid-phase microextraction (SPME) with gas chromatography?mass spectrometry (GC?MS).

Researchers from the University of Waterloo (Waterloo, Canada) designed and constructed a cold fiber solid-phase microextraction (SPME) device and applied it to the analysis of off flavors in a rice sample.

Supelco, a division of Sigma-Aldrich (St. Louis, Missouri), announced that its HybridSPE-Precipitation technology has won the SelectScience.net 2009 Scientists? Choice Award for Best New Separations Product in 2008.

Researchers from the Chinese Academy of Sciences (Beijing, China), Beijing Technology and Business University (Beijing, China), and Hebei University (Shijiazhuang, China) used dispersive liquid?liquid microextraction and ultrahigh-pressure liquid chromatography to analyze triclosan, triclocarban, and methyl-triclosan in aqueous samples.

Researchers from Universitat Rovira i Virgili (Tarragona, Spain) and the University of Strathclyde (Glasgow, UK) synthesized two molecularly imprinted polymers (MIPs) by precipitation polymerization using the antiepileptic drug carbamazepine as the template molecule and two types of crosslinking agents.

Scientists from the New Jersey Institute of Technology (Newark, New Jersey) used micro solid-phase extraction (SPE) devices consisting of single- and multiwalled carbon nanotubes packed in the needle of a syringe for sampling, analyte enrichment, and sample introduction.