Sample Preparation

The analysis of clozapine and norclozapine in plasma using automated on-line sample preparation and LC–MS/MS

In this installment, the subject of LPME is reviewed, with emphasis on the use of hollow fibers.

Discussing trends in sample preparation for the determination of phytochemicals in natural products.

The inventors of the QuEChERS technique present an update and a look at the future.

Selected modes of operations are presented and a few recent environmental applications of modular PLE are reviewed.

Selected modes of operations are presented and a few recent environmental applications of modular PLE are reviewed.

Associate Editor Megan Evans reviews this year's ASMS Conference, held in Salt Lake City, Utah.

Speaking about studies into electromembrane extraction and the possibilities that this alternative sample preparation technique opens up for research.

Ron Majors presents the second part of his yearly review of all that was new and innovative at Pittcon 2010, held this year in Orlando, Florida.

How the combination of an electroextraction with hollow-fiber liquid-phase microextraction can lead to a selective, rapid new method.

This article provides an introduction to electrochemical liquid chromatography mass spectrometry. The instrumental set-up is presented and selected applications in drug development processes are discussed.

The technique can be seen as an alternative to size-exclusion chromatography. This article illustrates how to choose parameters such as the dimensions of the separation channel and flow rates.

LCGC provides its annual editorial index as a resource for readers.

Peter Johnson gives readers the history of the well-known Minnesota Chromatography Forum.

In this installment of "MS-The Practical Art," guest columnist Jack Henion presents an historical and practical overview of lab-on-a-chip (LOC) research and the commercial achievement associated with it so far.

To meet system suitability requirements, chromatographers might need to make adjustments to the high performance liquid chromatography (HPLC) operating conditions.

Incognito presents the first in a series on the pitfalls in the practice of modern SPE.

Ron Majors provides first-hand coverage of some of the technology and application advances reported at HPLC 2009.

The former "Milestones in Chromatography" editor returns to give readers the story of his time in the field.

Ron Majors discusses the technique of Salting-out Liquid-Liquid Extraction (SALLE) and provides some examples of its successful applications.

A method of sample preparation followed by reversed-phase high performance liquid chromatography (RP HPLC) with diode array (DA) detection.

Doug Kitson looks at some of Poland's leading separation science groups.

Researchers from Vertox Laboratory, Defence Research and Development Establishment (Gwalior, India) used a liquid-liquid-liquid microextraction technique followed by liquid chromatography?mass spectrometry (LC?MS) to examine alkyl alkylphosphonic acids, which are important environmental markers of nerve agents.

Researchers from Banyu Pharmaceutical Co. (Ibaraki, Japan) used a novel extraction method to prepare drugs in gelatin capsules for analysis by high performance liquid chromatography.

A research group from AlbaNova University Center, Royal Institute of Technology (Stockholm, Sweden) developed an automated method for purifying and desalting proteins before mass spectrometry analysis.