Sample Preparation

Webinar Date/Time: Wed, Oct 15, 2025 11:00 AM EDT

Webinar Date/Time: Tue, Oct 7, 2025 11:30 AM EDT

Webinar Date/Time: Wed, Oct 8, 2025 11:00 AM EDT

Webinar Date/Time: Tuesday, September 30, 2025 8am PDT | 11am EDT | 4pm BST | 5pm CEST

In recent years, analytical chemists have increasingly adopted a sustainability viewpoint. Yet, at the same time, they still use traditional organic solvents for extractions and other procedures. In this installment of Sample Preparation Perspectives, we will look at solvent selection from green considerations. Trends on solvent use are presented, followed by a discussion on what makes a green solvent. Finally, the CHEM21 Solvent Selection Guide is examined as representative of tools for selecting green solvents for use in analytical methods and other chemical processes.

Webinar Date/Time: Thursday, July 17, 2025 8am PDT | 11am EDT | 4pm BST | 5pm CEST

A new dried spot-based technique involving untargeted liquid chromatography coupled with high-resolution mass spectrometry was testing for characterizing foodstuffs.

Webinar Date/Time: Tuesday, July 1, 2025 8am PDT | 11am EDT | 4pm BST | 5pm CEST

Webinar Date/Time: Thu, Jun 26, 2025 11:00 AM EDT

This article reports on new products introduced at Pittcon this year and in the preceding year related to sample preparation instruments, supplies, and accessories.

Webinar Date/Time: Mon, Jun 9, 2025 11:00 AM EDT

Analyzing trace compounds from complex samples often requires purification and pre-concentration, and online coupling of solid-phase extraction (SPE) with liquid chromatography (LC) helps minimize analysis time and solvent/sample use. Monoliths with large macropores are ideal for this coupling due to their low back pressure and versatility in various formats.

Michael Dong recently discussed sample preparation (SP) techniques for small-molecule drug substances and solid dosage forms.

Webinar Date/Time: Thursday, May 15, 2025 8am PDT | 11am EDT | 4pm BST | 5pm CEST

Webinar Date/Time: Tue, Jun 3, 2025 2:00 PM EDT

LCGC International spoke to Adrián de la Fuente and Silvia Valverde Bastardo from the University of Valladolid, Spain, about the development of a miniaturized headspace solid-phase microextraction gas chromatography–quadrupole time-of-flight mass spectrometry (HS-SPME-GC–QTOF-MS) method for the analysis of biogenic volatile organic compounds (BVOCs) emitted by native Spanish trees.

A new study, published by a researcher from Chemical Characterization Solutions in Minnesota, explored a new approach for sample preparation for the chemical characterization of medical devices.

Karolinska University Hospital researchers recently tested new approaches for analyzing drugs of abuse in oral fluids.

An automated solid-phase extraction (SPE) method has been developed to detect cyanotoxins in water.

Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.

This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.

Hydrophobic deep eutectic solvents have proven useful in extracting non-polar target compounds, though researchers have shown there is room for further development.

Webinar Date/Time: Wed, Apr 9, 2025 10:00 AM EDT

Aflatoxins are a family of toxins made by certain fungi that are found on agricultural crops, such as maize (corn), peanuts, and cottonseed.

Nadia Gadi and Allisson Barros de Souza spoke to LCGC International about their investigation into the application of electrochemical advanced oxidation processes (eAOPs) for the efficient removal of pharmaceutical residues in wastewater.