Application Notes: Food and Beverage
Analysis of 213 Pesticide Residues in Grapes by LC–MS/MS with Time-Managed MRM
September 1st 2018In this study, a fast, sensitive, and selective multiresidue method has been developed by coupling QuEChERS sample preparation with LC–MS/MS. Using time-managed-MRM™ in the QSight® triple quadrupole mass spectrometer, the optimum dwell time can be generated automatically for MRM transitions based on the number of coeluting transitions, expected cycle time, retention time, and tolerance time window of the targeted analytes. Such method automation results in improved data quality and better sensitivity, accuracy, and reproducibility, as demonstrated in this study by the results of 213 pesticide residues analyzed in grape samples.
Fast and Sensitive Analysis of Amino Acids Using Automated Pre-Column Derivatization
July 1st 2018The building blocks of peptides and proteins, amino acids, are present in animals, humans, and plants. The analysis of amino acids is of essential significance in several areas including food science, clinical diagnostics, and pharmaceutical products research. Classical liquid chromatography (LC) determination of amino acids is performed with sample pretreatment including pre-column as well as post-column derivatization to improve or enable spectroscopic detection.
Ethylcarbamate (Urethane) in Distilled Alcoholic Beverages
February 1st 2016A variety of alcoholic beverages purchased within the UK were analyzed for the presence of Ethylcarbamate. A 1 µL injection of these alcoholic beverages were analyzed on an Ellutia 200 GC followed by detection on an Ellutia 820 TEA working in nitrogen detection mode. This mode of analysis detects nitrogen containing compounds within a sample. The Ellutia 810/820 systems are able to analyse various nitro or nitroso compounds, utilizing the selectivity available through nitrogen or nitroso modes. Nitrogen mode utilizes the catalytic pyrolyzer tube, oxygen reactor, and higher temperatures to detect nitrogen compounds. Results for various alcoholic beverages are shown in Figure 3. The samples were found to have various low levels of ethylcarbamate, the system was optimized through levels of oxygen input and EHT sensitivity. The samples were then analyzed adopting a standard addition approach.