Application Notes: General

This application note demonstrates the scalability from analytical to semi-preparative mode while maintaining similar resolution between the two different capacity columns.

This two-step workflow allows for the rapid screening of N-linked glycans for upstream and downstream mAb production.

This application note demonstrates that FcγRIIIA affinity chromatography allows fast assessment of biologic activity and glycoform pattern of antibodies.

A wide variety of LC column chemistries were evaluated to demonstrate new chromatographic approaches to complex PFAS analyte lists.

Phenomenex announces a new graphitized carbob black (GCB) SPE tube for DOD QSM 5.3 compliant PFAS analysis.

Strata-SDB-L and Luna Omega 1.6 µm PS C18 demonstrate excellent precision and recovery in EPA Method 537.1 for the analysis of PFAS in drinking water.

Application guide to PFAS analysis in environmental and food samples, from sample preparation to LC–MS/MS analysis, featuring both validated and exploratory methods.

A novel LC approach to manipulate the chromatography of closely related PFAS analytes to separate co-eluties and avoid matrix interferences.

Validation of a water and wastewater method for the California PFAS panel using SPE (WAX/GCB) preparation and LC–MS/MS analysis with a variable pH LC mobile phase

Strata PFAS (WAX and GCB combined in a single SPE tube) compliant with DOD QSM 5.1, but more accurate, precise, and economical than dual tube or dispersed GCB solutions.

A QuEChERs + SPE sample preparation technique coupled with LC–MS/MS is shown to provide sub-ppb analysis of PFAS in dairy and fish samples.

In a commercial laboratory setting, Strata-X-AW and Gemini 3 µm C18 show excellent precision and recovery in EPA Method 533 for the analysis of PFAS in drinking water.

This white paper will illustrate how integrated pump controllers optimize pump performance by automatically controlling flow or pressure.

With a new electrochemical cell, complete reduction of inter- and intra-disulfide bonds in mAbs is achieved with superior sequence coverage.

LPGC–MS is a technique that uses the MS vacuum system, along with a specially designed column setup, to lower pressure inside the entire column, speeding up analysis.

This application note is suitable for the identification of sibutramine in crude material or finished products in a routine setup.

Learn the advantages of HILIC to measure and monitor glycosylation, deamidation, and oxidation, which are critical for the function and form of proteins and peptides.

Antiretrovirals have come back to the forefront of separation science at this moment in time, as they have found use in the fight against SARS-CoV-2.