Application Notes: General

This white paper will illustrate how integrated pump controllers optimize pump performance by automatically controlling flow or pressure.

With a new electrochemical cell, complete reduction of inter- and intra-disulfide bonds in mAbs is achieved. For cystine knots peptides, the sequence coverage was 100%.

The performance of hyaluronic acid is closely tied to its molar mass, intrinsic viscosity, and molecular conformation, quantified absolutely by multi-detector SEC.

Using sorptive extraction to extract aroma compounds from honey, with automated statistical analysis to uncover differences and determine markers of authenticity

The SI-36 4D does not require organic solvent to achieve the separation. Gradient conditions and phosphate ions are eluted within 15 minutes, so analysis time is short.

Monovalent and divalent cations in tap water were analyzed by IC YS-50.

Oxyhalides and anion standards in tap water were analyzed successfully using IC SI-52 4E. This is applicable to analyzing sources like rain, river water, and runoff.

The application successfully separates the 7 typical ions including F-, Cl-, NO2-, Br-, NO3-, PO43-, and SO42-, and it fulfills US EPA Method 300.1 (A) requirements.

This application introduces the automated analysis of fluorescent diastereomers of the proteinogenic D/L-amino acids using derivatizing reagents with chiral structures.

The seven main anions can be separated quickly using the IC NI-424 column. Improvement has been made in the separation of chloride and nitrite ions.

Fused-Core® Technology benefits PFAS analysis for fast, efficient, and rugged separations which are paramount to environmental analysis.

HALO® PFAS and PFAS Delay columns are application verified columns well suited for challenging environmental sample analysis.

High throughput analysis of 33 PFAS compounds found across EPA methods 533, 537.1, and 8327 in under 5 minutes.

HALO® PFAS delay and HALO® PFAS analytical columns deliver rugged, reproducible performance for the most challenging environmental sample matrices.

Rapid and high-resolution analysis of PFAS compounds across EPA methods 537.1, 533, and 8327, using the new HALO® PFAS delay and analytical columns.

Blood alcohol content is commonly analyzed in forensics; replacing helium carrier gas with nitrogen can provide the same quick, reliable, and accurate results.

This goal of this note is identity confirmation of protein-based impurities of a therapeutic protein by multi heart-cut 2D-LC–MS in a top-down experiment.