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Click the title above to open the LCGC North America June 2018 regular issue in an interactive PDF format.

A new type of analysis called “wide-selected ion monitoring (SIM)/MS2” scanning, is capable of screening for a wide range of DNA adducts (chemical modifications to genomic DNA). This method has successfully identified DNA adducts from carcinogen exposures and oxidative stress in human prostate and kidney tissues.

An important advantage of standardized methods is that they enable comparability between laboratories and across studies. In this work, the author used a standardized targeted kit to demonstrate the accuracy, sensitivity, and reproducibility of the approach, analyzing serum samples obtained from type 2 diabetes study subjects and healthy controls.

For the BTEX compounds, detection limits in the single-digit parts-per-billion concentration range (by volume) are readily achievable within seconds using selected ion flow tube mass spectrometry (SIFT-MS), because sample analysis is achieved without chromatography, preconcentration, or drying.

Our annual review of the ASMS national conference. This year’s event was held June 3–7 in San Diego, California.

This article describes a direct analysis of glyphosate, aminomethylphosphonic acid (AMPA), glufosinate, and 3-methylphosphinicopropionic acid (MPPA) in water by liquid chromatography coupled to tandem mass spectrometry (LC–MS/MS) without derivatization.

Researchers from Merck and Agilent Technologies have developed a simple and fast generic gas chromatography–flame ionization detection (GC–FID) method for the quantitation of volatile amines in pharmaceutical drugs and synthetic intermediates.

HILIC is not straightforward and there may be a number of mechanisms in play which need to be considered.

Click the title above to open The Column June 2018 North American issue, Volume 14, Number 6, in an interactive PDF format.

This Wednesday morning session will cover instrumental advances for improving signal-to-noise, digital waveform technology, ion mobility, and duty cycle, and for MS analysis of precursor and neutral loss scans and intact high m/z molecular ion analysis. It will be chaired by Randall E. Pedder of Ardara Technologies and will be held in Hall D from 8:30 to 10:30 a.m.

The award presentation for the Ron A. Hites award for an outstanding research publication in JASMS will take place on Wednesday at 4:45 pm, in Ballroom 20A on the upper level.

This Wednesday afternoon session on new research in informatics and metabolomics will be chaired by Xiaoyu Yang of NIST. It will be held in Ballroom 6CF on the upper level from 2:30 to 4:30 am.

This Wednesday afternoon session will present new research into the microbiome. It will be chaired by Trent Northern of Lawrence Berkeley National Laboratory and will be held in Ballroom 20A from 2:30 to 4:30 p.m.

This Tuesday morning session will discuss clinical and field applications of mass spectrometry, such as proteomic genotyping, detection of cancer tumors and metastases, tissue profiling, and therapeutic drug monitoring. It will be chaired by Alan Rockwood of Rockwood Scientific Consulting and will be held in Ballroom 6CF from 8:30 to 10:30 a.m.

Research awards will be presented this afternoon at 4:45 in Hall D, at the ground level, to Michael T. Marty of the University of Arizona and James S. Prell of Oregon State University. Marty received his PhD in 2013 at University of Illinois at Urbana-Champaign.

The 2018 recipient of the Biemann Medal is Benjamin A. Garcia for his contributions to elucidation of the “histone code,” the set of posttranslational modifications (PTMs) to histone proteins that are thought to regulate gene expression. His lecture will be given at 4:45 pm in Hall D, at the ground level.

This Tuesday afternoon session will discuss mass spectrometry analysis of emerging environmental contaminants found in fish, wastewater effluent, arctic snow, drinking water, and other matrices. It will be chaired by Eunha Hoh of San Diego State University and will be held in Ballroom 6A from 2:30 to 4:30 p.m.

What type of mass spectrometry (MS) instrumentation provides the best specificity during trace quantitative analysis from complex mixtures?

The 2018 recipients of the John B. Fenn Award for a Distinguished Contribution in Mass Spectrometry are Gert Von Helden, Martin F. Jarrold, and David E. Clemmer, for their pioneering contributions to the development of ion mobility spectrometry (IMS).

This Monday morning session explores the various issues that arise in the quality control laboratory. Jason Rouse of Phizer, Inc. will chair the session, which will be held in Ballroom 20 BC on the upper level, from 8:30 to 10:30 pm.

This Monday morning session will cover a variety of issues in petroleum and biofuel analysis. It will be chaired by Carolyn Hutchinson of Willamette University and will be held in Ballroom 6DE from 8:30 to 10:30 a.m.

This Monday afternoon session will present recent advances in mass spectrometry imaging in plants, animals, and humans. It will be chaired by Shama Mirza of the University of Wisconsin-Milwaukee and will be held in Ballroom 20A from 2:30 to 4:30 p.m.

This second of the two parallel tutorial sessions on Sunday evening includes talks from Gregory Eiden of Pacific Northwest National Laboratory (PNNL) and Jack Beauchamp of California Institute of Technology.

The ASMS conference will offer two parallel tutorial sessions on Sunday evening.

Both of these Plenary session talks will take place in Hall D, ground level.

Three one-day short courses will be held on Sunday, June 3, from 9:00 am–4:30 or 5:00 pm. Course registration and badge pick-up is at 8:00 am on Sunday, and lunch and refreshment breaks will be provided.