The Column
The development and commercialisation of new medical drugs is a complex and costly process, but increasing pressure is being placed on drug companies to accelerate the timeline from discovery of new drugs, through to clinical trials and then to their release onto the market. The pharmaceutical industry continues to demand ever more advanced products aimed at improving health and the quality of modern-day life.
The Column
Janet Kelsey of The Column spoke to Frédéric Cheviron, Sales & Marketing Manager for Chiral Technologies Europe, about the technology they use in drug development and how companies can improve their method development.
The Column
The design of strategies to reduce the activity of residual silanols in conventional alkyl-bonded columns is still one of the main challenges in the current separation of basic compounds by reversed-phase liquid chromatography.
The Application Notebook
Waters Application Note
The Application Notebook
Phenomenex Application Note
The Application Notebook
Waters Application Note
The Application Notebook
Phenomenex Application Note
The Application Notebook
Wyatt Application Note
The Column
Janet Kelsey of The Column spoke to Geofrey K. Wyatt of Wyatt Technology about MALS technology and how standards set by the European Pharmacopoeia dictate the type of instrumentation used for characterizing hydroxyethyl starch for pharmaceutical use. The advantages of using MALS instrumentation are also explained.
LCGC Asia Pacific
The various steps of an experimental design-based approach are considered and the problems that arise from wrong choices are described.
LCGC North America
A description of the use of UHPLC in the biopharmaceutical industry to characterize drug substances through peptide mapping and amino acid analysis
The Application Notebook
Agilent Application Note
The Application Notebook
Wyatt Application Note
The Application Notebook
Dionex Application note
The Application Notebook
Waters Application Note
LCGC Europe
The various steps of an experimental design-based approach are considered and the problems that arise from wrong choices are described.
The Column
Poplar buds could hold untapped potential as an ingredient in anti-ageing skin creams, a study has found.
The Column
Forensic Determination of Sildenafil and Vardenafil in Seized Evidence
The Column
Thin Layer Chromatography industrial distribution
LCGC North America
Isranalytica offered great talks on biotechnology, on topics from comprehensive protein characterization to middle-out proteomics to capillary electrophoresis for glycoprofiling.
The Column
Comprehensive two-dimensional gas chromatography is a powerful technology for separating complex samples and therefore is well suited for non-targeted analysis.
The Column
Dafydd Milton of Thermo Fisher Scientific, Runcorn, Cheshire, UK talks about the analytical challenges facing the pharmaceutical industry and developments made to overcome them.
LCGC Europe
Microextraction by packed sorbent is a sample preparation technique that can be connected on-line with LC or GC systems.
The Column
In this study, the method of two-dimensional comprehensive GC applying an ultra fast quadrupole mass spectrometer as detector was used (GC×GCqMS).
LCGC Asia Pacific
Demonstrating that flow field-flow fractionation can separate protein aggregates for preparative and analytical purposes.
