November 20th 2023
In this LCGC Blog, Muhammad Farooq shares some tips for entering different careers within the analytical chemistry industry.
November 10th 2023
Scientists from Egypt have developed a green reversed-phase high-performance liquid chromatography (RP-HPLC) method to determine the amounts of methionine and paracetamol in different mixtures.
November 8th 2023
To better understand the purity of therapeutic peptides, scientists from Germany, studied the effects supercritical fluid chromatography (SFC) could have during the analysis.
November 6th 2023
A team of scientists from Taizhou, China have developed a means of studying the medical effects of Qiangxin Lishui Prescription (QLP).
September 18th 2023
Scientists from the National Institute of Pharmaceutical Education and Research (NIPER) in India used a variety of techniques to characterize erdafitinib and its various products.
Improved Clean Up and Recovery of Pharmaceutical Compounds From Plasma Using Strata-X Solid Phase Extraction vs Traditional Liquid-Liquid Extraction
Phenomenex Application Note
Light Scattering for the Masses Liposome Characterization by FFF-MALS-QELS
Wyatt Application Note
A Matter of MALS
Janet Kelsey of The Column spoke to Geofrey K. Wyatt of Wyatt Technology about MALS technology and how standards set by the European Pharmacopoeia dictate the type of instrumentation used for characterizing hydroxyethyl starch for pharmaceutical use. The advantages of using MALS instrumentation are also explained.
Common Problems with Method Optimization in Pharmaceutical Analysis
The various steps of an experimental design-based approach are considered and the problems that arise from wrong choices are described.
Current Applications of UHPLC in Biotechnology Today, Part I (Peptide Mapping and Amino Acid Analysis)
A description of the use of UHPLC in the biopharmaceutical industry to characterize drug substances through peptide mapping and amino acid analysis
Analysis of Cholesterol Lowering Drugs (Statins) Using Dried Matrix Spots Technology and Poroshell 120 HPLC Columns
Agilent Application Note
LC Analysis of Aminoglycoside Antibiotics Kanamycin and Amikacin
Dionex Application note
Low Level Enantiomeric Impurity Analysis Using the Acquity UPSFC System
Waters Application Note
Poplar buds could hold untapped potential as an ingredient in anti-ageing skin creams, a study has found.
Forensic Determination of Sildenafil and Vardenafil in Seized Evidence
Market Profile: Thin Layer Chromatography
Thin Layer Chromatography industrial distribution
Biotechnology Highlights from Isranalytica 2011
Isranalytica offered great talks on biotechnology, on topics from comprehensive protein characterization to middle-out proteomics to capillary electrophoresis for glycoprofiling.
Non-targeted Cross-Sample Analysis with Comprehensive Two-Dimensional Gas Chromatography (GC×GC)
Comprehensive two-dimensional gas chromatography is a powerful technology for separating complex samples and therefore is well suited for non-targeted analysis.
The Challenges of Effective Analysis in The Pharmaceutical Industry
Dafydd Milton of Thermo Fisher Scientific, Runcorn, Cheshire, UK talks about the analytical challenges facing the pharmaceutical industry and developments made to overcome them.
On-line Whole Blood Analysis using Microextraction by Packed Syringe (MEPS) and LC–MS–MS
Microextraction by packed sorbent is a sample preparation technique that can be connected on-line with LC or GC systems.
Drug Screening using GC×GCqMS with Thermal Modulation
In this study, the method of two-dimensional comprehensive GC applying an ultra fast quadrupole mass spectrometer as detector was used (GC×GCqMS).
The Preparative Use of Flow Field-Flow Fractionation
Demonstrating that flow field-flow fractionation can separate protein aggregates for preparative and analytical purposes.
Several ZORBAX Rapid Resolution High Definition (RRHD) 1.8 µm Selectivities Facilitate Method Refinement
Light Scattering for the Masses Heparin Characterization
Direct Determination of 2-Ethylhexanoic Acid in Clavulante
Improving Mass Load Capacity for Basic Compounds Using Charged Surface Hybrid (CSH) Technology Columns
Rapid, Ultra-High Efficiency USP Assay for Ibuprofen Using Kinetex 2.6 µm XB-C18 Core-shell HPLC/UHPLC Column
High-Throughput Tools and Approaches for Development of Process Chromatography Steps
An overview of high-throughput process development (HTPD) tools and approaches, as well as a case study
Using UPLC Technology as a Method Development Tool for Isolation and Purification in Drug Discovery and Development
High Speed Analysis of Paracetamol and its Process Impurities
KNAUER Application Note
Glycoproteins and Biotechnology — Recombinant Biopharmaceutical Products: Identification, Characterization, and Chemical Equivalency?
Glycoproteins appear to have become the most common biopharmaceutical product today, and they also seem to be increasing in popularity and importance with time.
Electronic lab notebook
Agilent Technologies has announced that Merck-Serono has selected the company?s OpenLAB ELN to enhance scientific collaboration globally throughout R&D for finding new small molecules and biopharmaceuticals.
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