
This study reports a validated rapid, low-volume LC–MS/MS method capable of simultaneously quantifying remifentanil, etomidate, and rocuronium across a wide concentration range.

This study reports a validated rapid, low-volume LC–MS/MS method capable of simultaneously quantifying remifentanil, etomidate, and rocuronium across a wide concentration range.
LCGC International spoke to Pablo Mohaupt, who, along with Marie-Laure Pons and their colleagues at the Clinical Proteomics Platform of Montpellier (Montpellier, France) and Shimadzu Corporation (Duisburg, Germany) developed a mass spectrometry (MS)-based method to measure α-synuclein peptides in plasma, aiming to identify disease-specific biochemical signatures that could support earlier and more precise diagnosis of α-synucleinopathies.

In a joint study conducted by Harbin University of Commerce and Northeast Agricultural University, gas chromatography-mass spectrometry (GC–MS) was used to investigate the volatile compounds profiles and quality changes of soybean-based meat analogue under 4 °C and -18 °C storage conditions.

In this article, you’ll find some of the top content that was published on LCGC this week, including calls for new chromatography technologies and interviews with rising stars in the field.

Can thyme reduce inflammation caused by rheumatoid arthritis? Researchers at Koya University (Koya, Iran) used gas chromatography-mass spectrometry to find out.

Evelyn Rampler of the Department of Analytical Chemistry at the University of Vienna discusses how her team developed a robust LC–MS/MS platform for semiquantitative glycosphingolipidomics in barley, enabling detailed structural annotation of GIPCs across developmental stages and stress conditions, and paving the way for comparative analyses across plant species.

Submit your latest chromatography products—including HPLC, GC, columns, and software—for inclusion in our upcoming new products article.

Research conducted at the Central University of Venezuela (Caracas, Venezuela) resulted in the development of a robust, definite, and economical methodology for rapid and accurate quantification of theobromine and caffeine in cocoa beans extracts from Venezuelan cocoa.

LCGC International spoke to Evelyn Rampler of the Department of Analytical Chemistry at the University of Vienna about the insights yielded regarding the role of glycosphingolipids in plant physiology and environmental resilience.

In this article, you’ll find some of the top content that was published on LCGC this week, including our upcoming forensic science content series and an interview on preanalytical factors for ethanol testing.

In research performed at the Beijing Technology and Business University (China), the aroma compounds of duck broth stewed from seven parts were characterized by headspace solid-phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC-MS) and gas chromatography-ion mobility spectrometry (GC-IMS).

During National Forensic Science Week, on September 15, LCGC International will release a one-day online series titled, “From Sample to Verdict.” This series will spotlight how chromatography is contributing to the advancement of forensic analysis, and how innovation in analytical science is improving law enforcement and investigative practices in the modern era.

Researchers investigated the impact of HCO3 in water on the aroma of brewed tea infusions using sensory evaluation, headspace solid-phase microextraction, and gas chromatography-mass spectrometry (GC-MS) techniques

Researchers in Egypt aimed to develop an efficient in vitro regeneration system for a local stevia genotype using callus induction, as well as both direct and indirect micropropagation and to assess its impact on steviol glycoside accumulation by comparison with conventionally soil-grown plant.

During ASMS 2025, LCGC International covered the most notable news from corporate and individual attendees, highlighting the latest advancements in mass spectrometry.

The company plans to invest billions in a new drug manufacturing hub in Virginia, dedicated to chronic disease treatments, alongside additional facilities in California, Indiana, Maryland, Massachusetts, and Texas.

Researchers at Jiangmen Central Hospital (China) investigated the association between red blood cell folate and visceral adipose tissue in young and middle-aged adults in the United States using liquid chromatography-tandem mass spectrometry (LC-MS/MS).

The pharmaceutical industry’s move toward increased U.S.-based manufacturing is changing the landscape of career opportunities for analytical chemists.

Microplastics are everywhere. Crossing ecosystems and human tissues, research continues into their detection, behavior, and health impacts. This discussion aims to provide a short overview of recent microplastic research, and the chromatographic techniques utilized.

Researchers at the University of Wisconsin-Madison employed hydrophilic interaction liquid chromatography (HILIC) enrichment coupled with oxonium-ion triggered electron-transfer/higher-energy collision dissociation (EThcD) fragmentation to simultaneously profile novel endogenous and glycosylated neuropeptides in American lobsters.

LCGC International spoke to Damià Barceló at the University of Almeria to explore the technical and methodological barriers to microplastic analysis in complex environmental matrices.

LCGC International spoke to Ibraam Mikhail of the University of Tasmania, lead author of the paper resulting from a study where a compact capillary liquid chromatography (capLC) system was coupled with two small-footprint and portable single quadrupole mass spectrometers for the analysis of haloacetic acids (HAAs) in water samples.

A research team from the University of Sfax and the University of Almeria has published a review paper examining the analysis and fate of microplastics (MPs) in wastewater, sludge, and landfills.

In this article, you’ll find some of the top content that was published on LCGC this week, including details on the recent merger between Waters Corporation and BD Biosciences.

Research conducted by the University of California (San Francisco and Davis, California campuses) and the Harbor-UCLA Medical Center (Los Angeles, California) reported on the prevalence of new psychoactive substances (NPS) in roadway crash victims in California.

Research conducted at the University of Copenhagen (Denmark) investigated the relationship between chemical composition and consumer liking, using Vivino ratings as quality endpoints.

Waters Corporation is merging with BD’s Biosciences and Diagnostic Solutions business in a $17.5 billion deal to expand its capabilities in life sciences and diagnostics.

Researchers at the University of Caldas (Manizales, Caldas, Columbia) investigated the volatile organic compounds comprising the volatilome of Hass avocado peel, pulp, and seed grown in the northern Caldas (as well as avocados purchased from commercial sources), employing headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC–MS) for their extraction and identification.

Researchers speculating that exposure to paraben in early childhood is associated with changes in satiety hormones performed analysis of urinary methyl, ethyl, propyl, and butylparaben (MeP, EtP, PrP, BuP) levels in 4–6-year-old children, using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).

Researchers from the University of Campinas (Campinas, Brazil) and the Waters Research Center (Budapest, Hungary) introduced a rapid, automated method using laser-assisted rapid evaporative ionization mass spectrometry (LA-REIMS) with high-resolution mass spectrometry to fingerprint coffee samples and predict sensory properties. LCGC International spoke to Leandro Wang Hantao of the University of Campinas regarding their work and the paper that resulted from it.