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Splash fluid. 3d illustration, 3d rendering. | Image Credit: © Pierell - stock.adobe.com.

Petroleum contamination from leaking underground storage tanks, for example, is a significant concern for both the environment and human health. Thorough characterization of the contamination is required to form appropriate risk assessments and remediation strategies, but until now, the determination of total petroleum hydrocarbons (TPHs) in soil has typically involved a convoluted and labour-intensive process. In this article, the analysis of TPH in environmental media is simplified using flow-modulated GC×GC–FID with quantitation based on pre-defined compound groupings. This approach overcomes the drawbacks of conventional solvent fractionation approaches, by eliminating the need for sample fractionation and automating data processing workflows.

A joint study between York University and the University of Tehran evaluated conventional analytical methods, such as gas chromatography (GC), high-performance liquid chromatography (HPLC), and mass spectrometry (MS), as well as other emerging portable PAH detection technologies in hopes of significantly improving the health and safety of firefighters by reducing their long-term risks of cancer.

Researchers employed reflectance spectrometric analysis to quantify species-specific plumage coloration, and high performance liquid chromatography (HPLC) to elucidate the feather carotenoids of South Asian flameback woodpeckers to assess their pigment chemistries and genomic underpinnings.

This week, LCGC International published a variety of articles on hot topics in separation science. Some of the articles included in this week’s update explore topics such as the metabolic risk in horses, the bioactivities in chili pepper varieties, and a report on the analytical instrument market for Q2 2025. Below, we’ve highlighted some of the most popular articles that were published this week.

LCGC International spoke with Aristeidis S. Tsagkaris, associate professor in the Department of Food Analysis and Nutrition at the University of Chemistry and Technology in Prague (Czech Republic), about his team’s study analyzing 19 Italian-grown chili pepper varieties using ultrahigh-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.

This week, LCGC International published a variety of articles on hot topics in separation science. From a feature article on about the latest challenges in U.S. research funding to an article that recaps the latest HPLC products sent to market this year, we remain dedicated to sharing the latest in chromatographic advancements. Below, we’ve highlighted some of the most popular articles that were published this week.

A joint study conducted by the University of Copenhagen, the Technical University of Denmark, and the University of Cambridge explored a potential untapped archive from natural history collections (particularly specimens relating to historical beeswax) using liquid-chromatography-tandem mass spectrometry (LC-MS/MS) to examine a honeybee queen cell specimen from the 19th century.

The Erlenmeyer flask in the line with color range solvent using for analysis calibration curve of iron in waste water sample. The experiment in chemistry laboratory. | Image Credit: © Arpon - stock.adobe.com

In recent years, analytical chemists have increasingly adopted a sustainability viewpoint. Yet, at the same time, they still use traditional organic solvents for extractions and other procedures. In this installment of Sample Preparation Perspectives, we will look at solvent selection from green considerations. Trends on solvent use are presented, followed by a discussion on what makes a green solvent. Finally, the CHEM21 Solvent Selection Guide is examined as representative of tools for selecting green solvents for use in analytical methods and other chemical processes.

A review article written by researchers at Imperial College London (United Kingdom) explored the potential of volatile organic compounds (VOCs) as early, non-invasive biomarkers for Parkinson’s disease (PD), a neurodegenerative condition that currently lacks reliable diagnostic tools for early-stage detection. LCGC International spoke to Ilaria Belluomo of Department of Surgery and Cancer, Imperial College London and lead author of the review, about how chromatography and mass spectrometry played a part in the team’s research.