The Application Notebook-06-01-2015

The Application Notebook

Most proteins, particularly soluble and membrane-bound proteins expressed in the endoplasmic reticulum, are glycosylated. The extent and result of glycosylation varies.

The Application Notebook

Organochlorine (OC) pesticides are hydrocarbons with multiple chlorine substitutions primarily used as insecticides. OC pesticides do not break down easily as the chlorine-carbon bonds are very strong.

Supercritical fluid chromatography (SFC) is an evolutionary technology and a powerful tool for enantiomer separation when used in combination with chiral stationary phases (CSPs).

This method increases sensitivity and reduces data acquisition time for a subset of pharmaceuticals and personal care products from the original EPA Method 1694 specifications.

The Application Notebook

This application note demonstrates the comprehensive 2D-LC analysis of different types of beer. Nontargeted, multisample analysis (fingerprinting analysis) enabled a classification of the different types of beer analyzed.

The Application Notebook
Food & Beverage

June 01, 2015

Due to the highly polar nature of saccharides, the analysis of sugars is typically achieved using hydrophilic interaction chromatography (HILIC).

The Application Notebook
Food & Beverage

June 01, 2015

Organic arsenic compounds added to feed stocks of chicken and poultry pose serious environmental and ecological threats. National and worldwide health organizations, such as the United States Environmental Protection Agency and the US Food and Drug Administration, have recently implemented more stringent concentration limits for arsenic species in drinking water and foodstuffs.

The global demand for fish as a natural source of fresh animal protein, essential fats, minerals, and vitamins continues to rise with the human population.

The Application Notebook
Food & Beverage

June 01, 2015

In brewing, barley undergoes a malting process, the grain if first drenched to make it germinate and then dried in kilns to capture the sugar and flavor compounds for the brewing process.

Pain management LC analyses can be difficult to optimize due to the limited selectivity of C18 and phenyl-hexyl phases.

The Application Notebook

The physical properties and behavior of polymers depends strongly on the properties of the polymer molecules themselves

The Application Notebook
Pharmaceutical/Drug Discovery

June 01, 2015

Poly(lactic-co-glycolic acid) (PLGA) is a copolymer based on glycolic acid and lactic acid. The two monomer units are linked together by ester linkages and form linear polyester chains

CAPCELL CORE ADME S2.7 (ADME) is a column packed with a novel stationary phase of superficially porous silica (core shell particle) modified by adamantyl functional groups.

The challenging retention of polar organic acids in reversed phase conditions is accomplished using a unique multi-mode stationary phase.

Enhanced-fluidity liquids are organic solvents or organic–aqueous solvents mixed with high proportions of liquefied gases, such as carbon dioxide.

Reflectron lenses are used in time-of-flight (TOF) mass spectrometers to create an electrostatic field to alter ion flow, providing for a longer flight path and therefore greater resolution.

The main objective of this study was to evaluate the capabilities of gas chromatography (GC) with time-of-flight mass spectrometry (MS) for screening pesticides in fruits and vegetables using a purpose-built accurate-mass database.

Issue PDF
The Application Notebook

June 01, 2015

Click the title above to open the LCGC North America June 2015 Application Notebook, Vol 33 No s6, in an interactive PDF format.