Application Notes: General

With Antec Scientific’s new ground-breaking µ-PrepCell-SS, electrochemical reduction of disulfide bonds in peptides, proteins, mAbs, and other biopharmaceuticals becomes possible routinely in LC-MS workflows. • Fast and efficient reduction of S-S bonds • Robust on-line reduction in top-down and bottom-up Proteomics • Reagent free, no interfering DTT or TCEP, ideal for HDXMS • Superior peptide sequencing and S-S bond assignment

An effective enrichment method for glycopeptides were developed based on iSPE®-HILIC material. It opens a range of opportunities for glycoproteomics research.

Testing shows that Restek Long-Life ESI electrodes for Sciex Turbo V sources provide equivalent chromatographic performance to original equipment manufacturer electrodes over significantly longer lifetimes.

An efficient separation of polar and nonpolar lipid representatives was achieved utilizing iSPE®-HILIC material. The lipids were separated according to their polarity.

• Disaster recovery and business continuity plans are crucial for companies. • Most laboratories are not confident in their recovery and continuity plans. • When seeking solutions for system failures, consider regulatory guidelines.

In this application we show how to achieve the best separation and sensitivity for insulin UHPLC-MS analysis by using formic acid as a weak ion pairing agent.

This application note demonstrates the ability of Daicel’s CHIRALPAK® IA-3 to perform both chiral and achiral separations using SFC and Hydrobenzoin as a test compound.

Note discusses how labs can streamline operations and cut costs with on-sit gas generation.

A sensitive HPLC method allows analyzing cannabinoids, including THC and CBD, in hemp and hemp-containing products to ensure compliance with the 2018 Farm Bill