Gas Chromatography (GC)

As part of the upcoming Recent Advances in Gas Chromatography meeting, Nicholas Morley will look at how two-dimensional gas chromatography-time-of-flight-mass spectrometry analyzes pharmaceutical packaging.

Two-dimensional gas chromatography time-of-flight mass spectrometry (GCxGC/TOF-MS) and gas chromatography–time-of-flight mass spectrometry (GC-TOF-MS), two different gas chromatography techniques, will have their procedures and uses compared at the Science and Industry Museum, in Manchester, UK.

Researchers in China studied a new process for measuring aberrant metabolites.

Studies published over the last five years have focused on fully or semi-automated approaches and their applications in extraction of both organic and inorganic pollutants, while modern robotic tools and 3D printing are starting to make impacts.

Microfluidic devices are considered ideal for fabricating portable diagnostic equipment for point-of-care testing, but substrates more environmentally friendly than glass or plastics are attracting interest.

What critical components can help to resolve the separation challenges related to pesticides analysis in food?

HRMS is widely used in chromatography for analyzing complex mixtures. However, chromatographers should take note of the exponentially larger data set that HRMS provides before deciding whether to use the technique for the analysis they are conducting.

We offer troubleshooting tips for various gas chromatography (GC) detectors, as well as provide an overview of the different options chromatographers have when using a GC detector.

A new approach based on post-column in situ hydrogenolysis, and flame ionization was used here to improve characterization of volatile aldehydes. We review and describe that approach here.

What can chiral capillary GC do for you? The answer lies in what analysis one is attempting to accomplish. Here, we discuss the utility of chiral capillary GC and where the technique is most valuable, focusing on three application areas in particular.

A chronological examination of GC is presented here, with a look at where the technique is heading and how it can be used to advance environmental sustainability.

Giorgia Purcaro of the University of Liège discusses the advantages offered by the liquid chromatography–comprehensive multidimensional gas chromatography time-of-flight mass spectrometer/flame ionization detector (LC–GCxGC–TOF-MS/FID) method in the analysis of mineral oil.

This instalment explores the challenges involved in detecting the effluent from a capillary gas chromatographic column and summarizes the many detector options.

An overview of different approaches for the qualitative and quantitative analysis of polysorbates.

Understanding separation principles is the key to success. Here's why.

Sauce-flavor or sauce-aroma baijiu, one variant of a popular Chinese liquor, is treated with a fermentation starter called daqu, giving the concoction a unique taste profile, and scientists want more information about how it can inform the manufacturing of higher-quality baijiu.

Among the compounds of concern found in the samples were nicotine-related alkaloids, psychoactive cannabinoids, and chemicals that promoted inflammation of the respiratory system.

While both branched-chain fatty acids (BCFAs) and straight-chain fatty acids (SCFAs) were analyzed, the profiling of BCFAs was considered especially important for future metabolomics and lipidomics studies.

Photoionization detectors (PIDs) are attractive for their high sensitivity and fast response time, while cost-effective equipment has been sought for online monitoring of volatile organic compounds (VOCs).

A research team has investigated the impact of hydrophilic/lipophilic balance (HLB) on the porogenic properties of non-ionic surfactants for chromatographic separation.

Quality control of raw hazelnuts is already a highly specific process, but has limitations including operator influence, duration, and lack of standardization. AI is now assisting in quality decision-making using GC×GC analysis.

Researchers have recalibrated polyparameter linear free energy relationships (PP-LFERs) for low-density polyethylene (LDPE) passive samplers. By utilizing a robust regression method and reliable partition coefficients and solute descriptors, the recalibrated models exhibited improved predictive performance, accurately estimating LDPE-water and LDPE-air partition coefficients across a wide range of compounds.

Stephanie Rankin-Turner and colleagues at Johns Hopkins Bloomberg School of Public Health have recently performed research in Zambia indicating that mosquitoes are more attracted to humans who exhibit abundant levels of certain volatile carboxylic acids.

While most diapers do not contain all 15 polycyclic aromatic hydrocarbons (PAHs), the concentration of these compounds varies by manufacturer, and no disposable diaper is entirely free of PAHs.

The combination of deep eutectic solvents (DESs) and cellulose paper, according to the researchers, bridges a current gap in sustainable, paper-based sorptive phases.