Pharmaceutical Analysis

LCGC International spoke with Quang-Dong Bui, a second-year PhD student at Vrije Universiteit Brussels to discuss his work in oligonucleotide analysis.

The editors of LCGC International highlight open roles for scientists in pharmaceuticals, instrument manufacturing, and more.

This article describes the contents and associated calculations of CoAs for small-molecule drugs. It explains how these documents help to ensure drug quality in the supply chain.

We interview Serge Rudaz of the University of Geneva about the upcoming 34th International Symposium on Pharmaceutical and Biomedical Analysis.

Here are the top five articles that the editors of LCGC International published this week.

In this interview for ASMS 2024, Liusheng Huang of the University of California San Francisco discusses his upcoming presentation about performing microvolume analysis on antimalarial drugs.

Scientists from the University of Messina recently developed a new omega-3 fatty acid-based supplement and tested its effectiveness on metabolism and lipid profiles.

Researchers have utilized ultra-high performance liquid chromatography-tandem mass spectrometry (UH PLC-MS/MS) to monitor 5-Fluorouracil, a medication used to treat various cancers, in dried blood spots. This process offers a simpler, more efficient method than those in place involving the monitoring of plasma.

HRIM-MS has shown unique capabilities when used to analyze cyclic peptide therapeutics, and enhances the analysis of biopharmaceuticals by efficiently filtering out interfering compounds for direct analysis within a complex mixture. These findings demonstrate the technique's utility and versatility.

Here are the top five articles that the editors of LCGC International published this week.

Researchers at Enveda Biosciences are transforming nature into new medicines with their artificial intelligence (AI)-enabled industrial-scale drug discovery platform incorporating tandem mass spectrometry (MS/MS).

Element Materials Technology introduced its Rapid Response Pharmaceutical Testing Service, providing expedited testing and focusing on various requirements including active ingredients and final drug products, extractables and leachables, degradation production, and elemental impurities.

The company’s new service will provide expedited testing to customer around the world.

Webinar Date/Time: Monday, April 15, 2024 and Tuesday, April 16, 2024 Morning Session: 10:00am - 12:15pm Lunchtime Session: 12:30pm - 1:15pm Afternoon Session: 2:00pm - 4:00pm

This month we interview Shijia Tang, principal scientist at Genentech, South San Francisco, CA, USA, about her innovative research focusing on the analysis of polymers and nanomaterials used in pharmaceutical analysis. Shijia decribes the benefits of an innovative in-line mixing modulation method for 2D-LC she developed for polymer and oligonucleotide analysis. The advantages of SEC–MALS to explore aggregation mechanisms for therapeutic constrained peptides and mRNA-lipid nanoparticles and their aggregates are also discussed.

Webinar Date/Time: Thu, Jan 25, 2024 2:00 PM EST

In this LCGC Blog, Muhammad Farooq shares some tips for entering different careers within the analytical chemistry industry.

In this study, an efficient technique is described for extracting and quantifying barbiturates in serum samples, combining ultrasound and surfactant-assisted dispersive liquid–liquid microextraction (dLLME) with poly(ethylene oxide)-mediated stacking in capillary electrophoresis.

Scientists from Egypt have developed a green reversed-phase high-performance liquid chromatography (RP-HPLC) method to determine the amounts of methionine and paracetamol in different mixtures.

Webinar Date/Time: Thu, Nov 30, 2023 2:00 PM EST

Webinar Date/Time: Thursday, December 7, 2023 at 9am EST | 2pm GMT | 3pm CET Thursday, December 7, 2023 at 1pm EST | 12pm CST | 10am PST

To better understand the purity of therapeutic peptides, scientists from Germany, studied the effects supercritical fluid chromatography (SFC) could have during the analysis.

A team of scientists from Taizhou, China have developed a means of studying the medical effects of Qiangxin Lishui Prescription (QLP).

Webinar Date/Time: Wed, Nov 15, 2023 11:00 AM EST 3:00 PM GMT | 4:00 PM BST

Webinar Date/Time: Thu, Jan 11, 2024 11:00 AM EST