Pharmaceutical Analysis

Organic solvents are generally not compatible with ion chromatography (IC) systems. The approach presented here assists the use of organic solvents for sample preparation and provides a mechanism for the removal of the organic solvents from the chromatographic flow path.

Three analytical and two pre-treatment methods—gas chromatography–mass spectrometry (GC–MS), gas chromatography–tandem mass spectrometry (GC–MS/MS), and liquid chromatography–tandem mass spectrometry (LC–MS/MS) plus liquid-liquid extraction (LLE) and dried blood spot (DBS) —were compared for the quantitation and characterization of barbiturates.

Here is some of the most popular content posted on LCGC International this week.

Webinar Dates/Times: Friday, December 13, 2024 Morning Session: 12:30 pm GMT | 1:30 pm CET | 7:30 am EST Afternoon Session: 2:30 pm GMT | 3:30 pm CET | 9:30 am EST

Mithibai College of Arts scientists recently used liquid chromatography-tandem mass spectrometry (LC–MS/MS) for detecting nitrosamines in blood pressure medication.

Webinar Date/Time: Wed, Dec 11, 2024 11:00 AM EST

Scientists recently developed new GC/LC-Q-TOF/MS-based method for determining pesticides in Angelica sinensis, a traditional Chinese medicine.

LCGC International sat down with Faith Johnson of ECOLAB to discuss her career and work with the Females in Mass Spectrometry (FeMS) group.

The grant will be part of a new collaborative scientific initiative to address the need for standards that define the desired performance of lateral flow immunoassay test strips to detect illicit drugs in tablets and powders.

Nicholas Ingram of IQVIA Laboratories recently spoke with LCGC International about using high-resolution mass spectrometry (HRMS) to help monitor drug stability.

Webinar Date/Time: Thu, Nov 14, 2024 10:00 AM EST

Webinar Date/Time: Thu, Nov 7, 2024 11:00 AM EDT

Webinar Date/Time: Tue, Nov 12, 2024 11:00 AM EST

An illuminating session at the International Symposium on Chromatography focused on currents trends and misconceptions surrounding oligonucleotide analysis.

Navin Rauniyar and Xuemei Han of Tanvex Biopharma USA recently discussed how identifying product-related variants through characterization enables the recognition of impurities that compromise the quality and safety of drugs.

Separation and Characterization of Macromolecules 11 (SCM-11) will take place from 22–24 January 2025 in Amsterdam, The Netherlands.

As part of our ISC 2024 coverage, we recently interviewed Alexandre Goyon of Genentech about his research and his being awarded our Rising Stars of Separation Science Award for Outstanding Achievement in Pharmaceutical Analysis.

Alexandre Goyon specializes in developing advanced analytical methods to support new drug modalities.

The 34th International Symposium on Chromatography kicked off on October 6 in Liverpool, featuring two plenary sessions and an opening ceremony.

Universidad Católica del Maul scientists reviewed advancements made in using machine learning and MALDI-TOF-MS for predicting antimicrobial resistance in different materials.

Webinar Date/Time: Tuesday, October 29th, 2024 Morning Session: 1:30 pm GMT | 9:30 am EDT | 2:30 pm CET Afternoon Session: 5:00 pm GMT | 1:00 pm EDT | 6:00 pm CET

Webinar Date/Time: Wednesday, October 23rd, 2024 Morning Session: 14:30 pm BST | 9:30 am EDT | 15:30 pm CEST Afternoon Session: 16:30 pm BST | 11:30 am EDT | 17:30 pm CEST Thursday, October 24th, 2024 Morning Session: 14:30 pm BST | 9:30 am EDT | 15:30 pm CEST Afternoon Session: 16:10 pm BST | 11:10 am EDT | 17:10 pm CEST

Webinar Date/Time: Wed, Oct 16, 2024 10:00 AM EDT

In this article, we review some key considerations for chromatographic technique selection and method development across the full drug process.

Webinar Date/Time: Thu, Sep 26, 2024 11:00 AM EDT