Despite the theoretical promise of reduced plate heights (h) < 1, most modern UHPLC columns can only deliver plate heights in the range from 1.4 to 2.5. However, improved packing procedures, a better understanding of the colloidal properties of particle suspensions, and the study of the rheological behavior of packed beds and the final bed structure should lead us to practical solutions that can double the column efficiencies.
Is that peak “pure”? How do I know if there might be something hiding under there? In part I of this series, we explore some of the concepts behind peak purity assessments, describe some tools that are used in commercially available software for these assessments,
Five tips to help you get the most out of your LC–MS instruments and methods
We explore the careers and achievements of the winners of LCGC’s 11th annual awards: Ronald E. Majors and Zachary S. Breitbach.
Here, a procedure is described for preparing polydisperse polymer standards to validate the accuracy of any SEC method for aqueous or organic mobile phases. This approach can be used for all calibration procedures with the exception of online light scattering and viscometric detection.
Click the title above to open the LCGC Europe February 2018 regular issue, Vol 31, No 2, in an interactive PDF format.
Click the title above to open the LCGC North America February 2018 regular issue, Vol 36 No 2, in an interactive PDF format.
I always think of a conference presentation to be like a rock band concert. Sure, the band is going to play some of their biggest hits, but they also want to propagate their new stuff. More importantly, they want to put on a show so that people are entertained. I do think there should be more emphasis on entertaining the audience during oral presentations.
Carolin Huhn was awarded the inaugural 2018 LCGC Europe/HTC Innovation Award on 25 January 2018 at 15th International Symposium on Hyphenated Techniques in Chromatography (HTC-15) in Cardiff, UK.
A new year means a fresh start. Incognito suggests some resolutions to help chromatographers succeed in 2018.
Researchers from the Liverpool School of Tropical Medicine and the University of Warwick have conducted a pilot study to assess the viability of a GC–IMS for the analysis of volatile organic compounds (VOCs) in exhaled breath for the diagnosis of bacterial respiratory tract infections (RTIs) in hospital patients.
Biotage AB (Uppsala, Sweden) has agreed a deal to purchase all outstanding shares in Horizon Technology Inc. for $18.4 million.
Researchers have developed a proteomics‑based approach, using liquid chromatography tandem mass spectrometry (LC–MS/MS), to identify the food sources of the Chagas disease vector Triatominae insects.
Click the title above to open The Column January 2018 North American issue, Volume 14, Number 1, in an interactive PDF format.
Click the title above to open The Column January 2018 Europe & Asia issue, Volume 14, Number 1, in an interactive PDF format.
Researchers from the Harbin Institute of Technology, Harbin, China, have developed a simple method for the extraction of organochlorine pesticides (OCPs) from river water samples using magnetoliposomes as adsorbents and gas chromatography tandem mass spectrometry (GC–MS/MS).
A Wednesday morning seminar and workshop starting at 9:00 am includes a talk by Noelle DeStefano of Duke University titled “Characterization of Organic Micropollutants in Ship Ballast Water by LC–High Resolution Accurate Mass Spectrometry.” The talk will take place at 10:15 am in Room 381 C.
On Wednesday, January 17, Jamie Schenk, a PhD candidate at The University of Texas at Arlington, will present a talk titled “Analysis of Hydraulic Fracturing Additives by Gas Chromatography and Liquid Chromatography.” The presentation is scheduled to take place at 9:00 a.m. in Room 381 B.
On Wednesday, January 17, Francois Huby of The Dow Chemical Company will present a talk titled “Comparative Evaluation of ‘Carbon Centric’ Gas Chromatography Detectors for Volatile Organic Compounds Analysis.” The presentation is scheduled to take place at 10:55 a.m. in Room 372 D.
On Wednesday, January 17, Tiffany Liden, a graduate student at the University of Texas at Arlington, will present a talk titled, “Characterization of Produced Water and Current Treatment Options.” The presentation will take place at 10:30 am in Room 381B.
Sometimes troubleshooting a separation can rely upon the end user spotting subtle clues within the chromatogram, and at other times the visual signs can be much more obvious. To start the New Year, I wanted to share some of the most common issues that we see with peak shapes in gas chromatography in the hope that if you spot some of these in your own work, you may be able to intercept problems and deal with them more effectively.