PharmTech LCGC Sciex Webinar 11.10

Webcasts

Sample Preparation Strategies for the Bioanalysis of Oligonucleotide Therapeutics

Webcast

***Live: Monday, November 9, 2020 at 11am EST| 8am PST| 4pm BST| 5pm CET *** Join us for this webcast to learn about sample preparation strategies for oligonucleotides bioanalytical workflows, including optimization of sample pre-treatment and solid-phase extraction for different types of oligonucleotides, how to approach extraction depending on different types of biological matrices, including solid tissue, and alternative sample preparation strategies using hybridization extraction. ***On demand available after final airing until Nov. 9, 2021***

Miniaturized Separations and Increased Sensitivity—What to Expect When Moving to Micro- and Nano-Scale HPLC

Webcast

***Live: Thursday, November 12, 2020 at 11am EST| 8am PST| 4pm GMT| 5pm CET*** What can you expect when moving to micro- and nano-scale HPLC? Join us for this webcast to learn about tools for micro- and nano-scale HPLC that are now available, in terms of new column technologies, injection modes (trap and elute), and separation condition strategies, and even connection systems that can help with the miniaturization of analytical scale separations to micro and nano scale. ***On demand available after final airing until Nov. 12, 2021***

The Importance of Reliable THC Concentration and the Role of Analytical Data

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***Live Dates: Tuesday, November 10, 2020 at 2pm EST| 1pm CST| 11am PST, and Thursday, November 12, 2020 at 2pm EST| 1pm CST| 11am PST***Learn the importance of accurate and reliable THC and CBD concentration results and the tools available to provide that data from an industry insider. ***On demand available after final airing until Nov. 12, 2021***

High Resolution GC–QTOF-MS for Routine Analysis of Dioxins and Targeted and Untargeted Screening in Environmental Matrices

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***Live: Thursday, Nov. 5, 2020 at 11am EST| 8am PST| 4pm GMT| 5pm CET*** In this webinar, we will report about validating a GC–QTOF-MS method to meet and exceed the performance characteristics of EPA 1613 for analysis of dioxins and other regulations. Furthermore, we will discuss a workflow combining targeted and non-targeted screening for analysis of environmental contaminants in water. On demand available after final airing until Nov. 5, 2021

Intact and Subunit MAM Assays Accelerate the Development of Antibody-Drug Conjugates

Webcast

***Live: Tuesday, November 3, 2020 at 11am EST| 8am PST| 4pm GMT| 5pm CET*** In this webcast, learn how multi-attribute assays were used to accelerate routine workflows for biotherapeutics characterization at the intact and subunit level. This new streamlined approach increased the efficiency to perform stability assessment of antibody-drug onjugates (ADC) significantly. *** On demand available after final airing until Nov. 3, 2021.***

Everything You Need to Know About Filtration

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***Live: Friday, October 30, 2020 at 11am EST | 8am PST | 3pm GMT | 4pm CET*** Join us to learn how to correctly select a filter for your application allowing you to avoid some of the common pitfalls related to filtration. *** On demand available after final airing until Nov. 30, 2021.***

Maximizing Your HPLC Method Development

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***Live:Tuesday, November 10, 2020 at 8am EDT | 1pm BST | 2pm CEST, and Tuesday, November 10, 2020 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST *** Please join us and Kathryn Lawson-Wood to discuss the importance of RP-HPLC phase chemistries, describing their key benefits, and typical applications for the best method-development approach to observe changes in selectivity. *** On demand available after final airing until Nov. 10, 2021.***

Simple and Fast: Novel Fc-Receptor Affinity Chromatography  for Antibody Characterization

***Live: Wednesday, October 28, 2020, 11am EDT| 8am PDT| 3pm GMT| 4pm CET*** Discover a new and unique tool to assess the variances in mAb glycoforms and their differences in potency and efficacy using an affinity Fc-Receptor based chromatographic methodology. Data obtained can be correlated to ADCC activity. *** On demand available after final airing until Oct. 28, 2021.***

Advanced Proteometic Workflows Using micro Pillar Array Columns: Insights of “The Proteome Landscape of the Kingdom of Life

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***Live: Tuesday, October 13, 2020 at 9am EDT| 2pm BST| 3pm CEST*** Johannes Müller, PhD student at the Matthias Mann group in Munich, will explain how the proteome landscape of the kingdoms of life have been concluded and how the µPAC™ column was used to setup an advanced proteomic workflow that was applied in this study. *** On demand available after final airing until Oct. 13, 2021.***

Characterization of Viral Vector Particles with LC–MS

*** Two Live Events! Monday, Oct. 26, 2020 at 9am EDT| 1pm GMT| 2pm CET and Monday, Oct. 26, 2020 at 2pm EDT| 1pm CDT| 11am PDT*** Join us for this web seminar to learn about the utility of mass spectrometry for characterizing adeno-associated viruses (AAVs), including how intact mass spectrometry can accurately confirm AAV capsid proteins, how AAV post-translational modifications can be identified and confirmed, and how upfront sample preparation can improve mass spec accuracy and resolution. ***On demand available after final airing until Oct. 26, 2021***

Chromatography Theory and Applications: A Virtual Symposium

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***Live: Two Day Event! Day One: Thursday, Oct. 22, 2020 10am EDT | 12:30pm EDT | 2pm EDT & Day Two: Friday, Oct. 23, 2020 10am EDT | 2pm EDT *** In this two-day online event, speakers will discuss theory and applications of gas chromatography (GC) and high performance liquid chromatography (HPLC). We have a morning and afternoon session each day, plus a lunchtime tutorial session on 2D-GC on Day 1. There will be live Q&A for the morning sessions and the tutorial. Attendance is free..*** On demand available after final airing until Oct. 23, 2021.***

Breakthroughs in FFF-MALS – New Levels of Performance and Usability

*** Three Events: Tuesday, Oct. 27, 2020 at 11am EDT| 8am PDT| 3pm GMT| 4pm CET Asia Pacific: Wednesday, Oct. 28, 2020 at 10:30 am IST| 1pm CST| 2pm JST Europe: Wednesday, Oct. 28, 2020 at 9am| 10am CET*** Characterizing complex nanoparticles, polymers and biotherapeutics is about to get a lot easier. ***On demand available after final airing until Oct. 28, 2021***

Applications of Separation and Mass Spectrometric Techniques for Challenges in the Analysis of Per- and Polyfluorinated Alkyl Substances (PFAS) in the Environment

***Live: Wednesday, Oct. 14, 2020 at 1pm EDT| 12pm CDT| 10am PDT*** Learn how PFAS have evolved in their use and pose analytical challenges, and how to use the benefits of superficially porous particles and LC–MS separations to overcome the challenges they present.*** On demand available after final airing until Oct. 14, 2021.***

Forever Chemicals: Understanding Their Origins, Evolution, and The Benefits of Superficially Porous Particle Column Technology in Overcoming the Analytical Separation Challenges They Present

***Live: Friday Oct. 16, 2020 at 2pm BST| 3pm CEST*** Join Dr. Stefano Polesello of the Water Research Institute (IRSA-CNR) and Dr. Andrew Harron of Advanced Materials Technology for a discussion on the pervasive nature of PFAS in our aquatic and agricultural systems, the analytical challenges it presents to those investigating it and how using superficially porous particle LC column technology solution provides benefit to LC–MS separations and elimination of background contamination of PFAS. *** On demand available after final airing until Oct. 16, 2021.***

Help! My GC Column isn’t Performing: Tips on Optimization and Care

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Whether you are new to working with GC columns, or as a seasoned GC veteran, you would like to refresh your skills and gain some additional knowledge and advice, this GC Webinar will give you practical tips and tricks on troubleshooting GC columns and keeping them at their peak performance. Presenter Gustavo Serrano will walk you through the webcast, covering a range of topics aimed at helping you improve your GC columns analysis. Live: Thursday, Oct. 8, 2020 at 8am EDT| 1pm BST| 2pm CEST Thursday, Nov. 12, 2020 at 8am EST| 1pm GMT| 2pm CET On demand available after final airing until Nov. 12, 2021

Dramatically Improve Dioxin Testing Productivity with a Single, Faster GC Column Solution for Food and Environmental Samples

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Register today to expand your knowledge on new and unique GC column solutions for faster and better analysis of persistent organic pollutants like dioxins in food and environmental samples. Learn how new GC column phases can greatly shorten method run time and increase sensitivity lab productivity as a single-column solution, making GC column selection a less painful proposition. Live: Tuesday, Oct. 20, 2020 at 11am EDT| 8am PDT| 4pm BST| 5pm CEST On demand available after final airing until Oct. 20, 2021

Method Development for the Characterization of Synthetic Oligonucleotides by LC-MS

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In this presentation, we will demonstrate the impact of mobile phase optimization on chromatographic separation and MS sensitivity and spectral quality. Additionally, we will look into how temperature and flow-rate can impact oligo separations as well. Live: Thursday, October 1, 2020 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST On demand available after final airing until Oct. 1, 2021

Overcoming the Challenges of Nitrosamine Impurities in Drugs

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The low levels at which the nitrosamine impurities occur in pharmaceuticals products creates analytical challenges for accurate determination. In this webinar we will discuss effective GC–MS approaches that provide high selectivity and sensitivity to fulfill the current regulations and enable a broader scope of analysis and future-proof results. Live: Tuesday, Oct. 13, 2020 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST On demand available after final airing until Oct. 13, 2021 Register free

Integrated Laboratory Informatics Systems Deliver Greater Efficiency and Improved Data Integrity

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Have you ever wondered what a fully integrated laboratory informatics system would look like, and the benefits it would provide your lab? Join us for this webcast to learn about such systems and considerations you should take when purchasing one for your lab. Live: Tuesday, Oct. 6, 2020 at 1pm EDT | 12pm CDT | 10am PDT Wednesday, Oct. 21, 2020 at 9am EDT | 2pm BST | 3pm CEST On demand available after final airing until Oct. 21, 2021 Register free

Building a More Efficient Routine Lab: Approaches to Modernizing HPLC Methods with New Technologies

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Listen and learn as Dr. James Grinias from Rowan University and Dr. Frank Steiner from Thermo Fisher Scientific discuss approaches and considerations to modernizing HPLC methods to increase throughput using superficially porous particles. They also discuss challenges in method transfer and describe new compliant hardware technologies built into the modern HPLC and UHPLC systems. Live: Monday, September 21, 2020 at 9am EDT| 2pm BST| 3pm CEST, Friday, September 25, 2020 at 2pm EDT| 1pm CDT| 11am PDT On demand available after final airing until Sept.. 25, 2021 Register free

Sponsored Content

Learn how to simplify the complexity of dioxin analysis using a fully integrated workflow based on GC–triple quadrupole analysis. This Dioxin Analyzer not only takes advantage of the new GC–MS/MS technical advancements, but significantly improves the ease of use and accelerates the implementation in routine laboratories. Live: Thursday, Sept. 3, 2020 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST On demand available after final airing until Sept. 3, 2021 Register free

Process Analytical Technology (PAT): Online Monitoring and Control of Upstream Titer, Product Quality and Amino Acid Content Using 2D-LC with SegFlow Interface

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Biopharmaceutical companies are transitioning from “quality-by-testing” philosophy to “quality-by-design” paradigms, and establishing QbD-based PAT tools to increase product and process understanding. Due to the deficit of analytical methods to support QbD-driven continuous bioprocessing, biopharmaceutical companies are actively developing PAT tools to comply with QbD regulations. Europe Broadcast: Wednesday, Sept. 30, 2020 at 9am EDT | 2pm BST | 3pm CEST US Broadcast: Wednesday, Sept. 30, 2020 at 2pm EDT | 1pm CDT | 11am PDT On demand available after final airing until Sept. 30, 2021.