Mass Spectrometry

A newly published review reveals insights into the history of capillary electrophoresis, from its development to its current state-of-the-art applications, through a comprehensive bibliometric analysis of publications between 1980 and 2021.

A review article describes spatial metabolomics using high spatial resolution mass spectrometry imaging (MSI), a promising technology that enables the visualization and analysis of metabolites at the cellular and subcellular levels.

Recent advancements in electrospray ionization mass spectrometry (ESI-MS) for single-cell proteomics are highlighted in a review article, including various separation techniques and MS instrumentation used to improve sample throughput and coverage.

New GC–MS research suggests that the presence of hemicellulose impurities in α-cellulose extracted from land plants may compromise reliable application of the 18O/16O ratio for environmental, physiological, and metabolic studies.

A new study evaluated the use of HILIC for fast aqueous species distribution analysis of Nickel(II)-Histidine complex, finding that HILIC is appropriate for investigating coordination metal complexes.

Researchers have now used mass spectrometry imaging to study induced pluripotent stem cells (iPSCs) during the early stages of differentiation.

A new approach combining high performance liquid chromatography–mass spectrometry with ultrafiltration, along with enzyme channel blocking and directional enrichment, has been found effective for screening natural histidine decarboxylase inhibitors in Radix Paeoniae alba, while reducing both false-positive and false-negative results.

Every year, the American Society for Mass Spectrometry (ASMS) presents Research Awards, the Research at Primarily Undergraduate Institution (PUI) Award, and Postdoctoral Career Development Awards. This year's winners will be honored at the 2023 ASMS Conference in Houston, Texas, from June 4–8.

A desorption electrospray ionization mass spectrometry (DESI-MS) method has been developed to effectively analyze historical synthetic dye samples.

In the first of a two-part series, a recent study discusses a new strategy for assessing the peak purity of pharmaceutical peptides analysis using 2D-LC–MS.

A recent study analyzed individual hippocampal cells at ultrahigh mass resolution using a FT-ICR mass spectrometer.

Brandon Ruotolo will receive the Biemann Medal at the 2023 ASMS Conference in Houston, Texas, which takes place June 4–8.

Joshua Sharp will receive the Ron Hites Award at the 2023 ASMS Conference in Houston, Texas from June 4–8.

Carol V. Robinson of the University of Oxford has been named the 2023 recipient of the ASMS John B. Fenn Award for Distinguished Contribution in Mass Spectrometry. Robinson will receive the award at the 2023 ASMS Conference in Houston, Texas, which takes place June 4–8.

Webinar Dates/Times: Session 1 (EU): Wednesday, May 17th, 2023 at 2pm BST | 3pm CEST | 9am EDT Session 2 (NA): Wednesday, May 17th, 2023 at 1pm EDT | 10am PDT | 6pm BST Session 3 (APAC): Thursday, May 18th, 2023 at 12pm JST | 11am CST | 11pm EDT

A new study tested different solvents and buffer additives for ion mobility spectrometry to test their impact on results.

Scientists have discovered that combining imaging mass spectrometry and microscopy can enhance molecular visualization.

Glyphosate and AMPA are two potentially dangerous chemicals within herbicides. Using LC–MS to detect these chemicals is important to human and environmental health.

Using LC–MS, scientists have developed a new method for testing doping steroids in blood.

A new method was recently developed that has the potential to revolutionize the use of piezoelectric atomizers in MS analysis, and ultimately provide a more efficient and superior soft ionization approach for the direct analysis of a variety of samples, including aqueous solutions.

The American Society for Mass Spectrometry will recognize twenty graduate students and ten undergraduate students for their academic achievements and mass spectrometry research.

The Al Yergey Mass Spectrometry Award, which recognizes scientists who make great contributions to mass spectrometry–based science, will be given to three "unsung heroes" this year.

Webinar Date/Time: Airing 1: Thursday May 11, 2023 at 10am EDT | 3pm BST | 4pm CEST Airing 2: Thursday May 11, 2023 at 3pm EDT | 2pm CDT | 12pm PDT

Combining liquid chromatography (LC) with high resolution mass spectrometry (HRMS) has led to incredibly detailed results in forensic drug screenings, though not without challenges.

Chemical isotope labeling (CIL) can lead to excellent biological sample analysis when combined with mass spectrometry (MS).

Direct-infusion tandem mass spectrometry (DI-MS/MS) enables researchers to quantify citrate isomers and isobars in biological samples with high accuracy and reliability.

Using an Analytical Quality by Design approach, scientists recently identified impurities in a pharmaceutical product for hypertension treatment.

Scientists recently used continuous electrospray ionization mass spectrometry to study what makes the inland taipei snake venom so dangerous.

Using liquid chromatography-tandem mass spectrometry, scientists have found a similarity between the protective functions of the oral permeability barrier and the skin barrier.

A new study that uses native top-down fragmentation and isotope depletion-mass spectrometry contributes to the growing body of research on αSyn and its association with Parkinson’s disease.