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Click the title above to open The Column December 2018 European/Asia issue in an interactive PDF format.

Selected highlights of innovative chromatography products.

A team of French researchers have demonstrated a new mass spectrometry technology based on nanomechanical resonators that is capable of measuring the mass of particles mega- to giga-dalton range.

Crawford Scientific has announced the acquisition of Anatune Ltd.

The analysis of skeletal remains using GC–MS from Gaul settlement excavations in Southern France has confirmed the ritualistic practice of head embalming in ancient Gaul culture.

Peak Scientific and Macfarlane Packaging have been awarded the “Supply Chain Solution of the Year Award” at the 2018 UK Packaging Awards.

Incognito scrutinizes the behaviour of baby boomers and Generation X, Y, and Z in the laboratory. What do they want from the workplace?

Liquid chromatography separations using gradient elution have the potential to be faster, give better detection limits, and have more flexibility than separations using isocratic elution. However, problems can occur with gradients. Some of these problems are inherent to the technique but can be avoided or accommodated with a little care. Others result from a poor understanding of gradient elution. In this new e-book, John Dolan, renowned LC expert and the longtime author of the "LC Troubleshooting" column in LCGC, presents the secrets to achieving success with gradient separations.

LCGC, the leading resource for separation scientists, is proud to announce that Milos V. Novotny and Ken Broeckhoven are the winners of the 12th annual LCGC Lifetime Achievement and Emerging Leader in Chromatography Awards, respectively. Novotny and Broeckhoven will be honored in a symposium as part of the technical program at the Pittcon 2019 conference in Philadelphia on March 18, 2019.

From May 12 – 17, 2019 at the Hilton Ft. Worth in Ft. Texas, I will be co-chairing (together with my colleague Prof. Dan Armstrong) the 43rd International Symposium on Capillary Chromatography (ISCC) and the 16th GCxGC Symposium. I am writing to tell you this not only because organizing a meeting is quite an undertaking, but also because I am really excited about how this event is shaping up.

Click the title above to open the LCGC North America December 2018 issue in an interactive PDF format.

Click the title above to open the LCGC North America December Special Issue, Corporate Capabilities 2019, in an interactive PDF format.

Sample preparation is the most crucial step for the development of an analytical method. The main purpose of sample preparation is the extraction and preconcentration of the target analytes, as well as the removal of the matrix interferences, before their separation and determination. It is the most time consuming step that should be deliberately optimized to enhance extraction selectivity and detection capability. LLE and SPE, along with their variations, are usually applied for sample extraction and cleanup. MIPs can replace conventional sorbent materials in sample preparation techniques such as SPE, SMPE, and MSPD, offering increased selectivity over the target analytes. Attention is given in MISPE, which is mostly used to study MIP applications, as well as a commercially available technique.

Lloyd Snyder was one of perhaps ten “founding fathers” of high performance liquid chromatography (HPLC), with seminal publications in most areas, including adsorption (normal phase), reversed phase, isocratic, gradient, and preparative chromatography; plus solvent, temperature, and column selectivity. With nine books, several hundred publications, and an h-index of 83, he was one of the most widely cited chromatographers and received many of the most prestigious awards in separation science.

Click the title above to open the LCGC Europe December 2018 regular issue in an interactive PDF format.

The 48th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2019) will be held 16Ð20 June 2019 at the Milano-Bicocca University, Milan, Italy. This is the first time that this Symposium will be held in Italy.

The fundamental principles of UV detection

The fundamental principles of UV detection are explained, in a single page.

An ultraviolet (UV) detector signal can be an excellent source of clues for troubleshooting problems with your LC-even if you are using a mass spectrometer. We also share another good source of clues.

Lloyd Snyder was one the “founding fathers” of high performance liquid chromatography (HPLC). He was one of the most widely cited chromatographers with many important contributions to the field of separation science.

The 2019 ISCC and GCxGC Symposia, May 12–17, 2019, in Fort Worth, Texas, promise to provide an exciting and relevant venue for discussions of the latest developments in chromatography.