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Click the title above to open LCGC Europe Supplement December 2019, Volume 32, Number 12, in an interactive PDF format.

Click the title above to open The Column December 2019 Europe & Asia issue, Volume 15, Number 12, in an interactive PDF format.

Click the title above to open The Column December 2019 North American issue, Volume 15, Number 12, in an interactive PDF format.

The Eastern Analytical Symposium (EAS) Award for Outstanding Achievements in Chemometrics was presented to Peter de Boves Harrington on Tuesday 19 November.

Selected highlights of innovative chromatography products.

Researchers from the University of Leipzig have used gas chromatography–mass spectrometry (GC–MS) to study the fertility cues of non-human primates.

The Eastern Analytical Symposium (EAS) Award for Outstanding Achievements in the Fields of Analytical Chemistry was presented to Joel M. Harris at EAS 2019 on Wednesday 20 November.

Thermo Fisher Scientific has announced a collaboration with Owlstone Medical to advance the early diagnosis of cancer and other diseases utilizing novel biomarkers and non-invasive breath sampling.

What does a best-in-class laboratory workplace look like?

I’ve been dealing recently with issues in the laboratory when using ammonium acetate buffers, including surprising rises in HPLC–MS back pressures when starting the instrument after overnight storage, as well as difficulties with MS sensitivity.

To fully characterize a protein biopharmaceutical, it must be broken down into smaller segments (peptides). Several high performance liquid chromatography (HPLC) techniques can be used to provide a wealth of information on everything from post-translational modifications (PTMs) to the glycoprofile to information on similarity when characterizing biosimilars.

I run into scientists all the time who have never heard the term exposome. Most are not intimately connected in the analytical world; these days, analytical scientists seemingly expect “ome” and “omics” to be tacked onto pretty much anything.

Click the title above to open the LCGC Europe December 2019 regular issue, Volume 32, Number 12, in an interactive PDF format.

Click the title above to open the LCGC North America December supplement, Corporate Capabilities 2020, Volume 37, Issue s12, in an interactive PDF format.

Click the title above to open the LCGC North America December 2019 issue, Volume 37, Number 12, in an interactive PDF format.

Chromatographic peak integration continues to be a major regulatory issue and was first discussed in this column in 2015. Is the approach to manual intervention and manual integration outlined still acceptable in the light of regulatory citations and guidance documents published since then?

The 44th International Symposium On Capillary Chromatography (ISCC) and 17th GC×GC Symposium will be held at the Palazzo dei Congressi, in Riva del Garda, Italy, from 24–29 May 2020.

This technical overview of chromatography data systems (CDS) looks at how CDS are designed, how they can be used most effectively, and what developments we can expect in the future.

The potential of food packaging components to migrate into food is an important health concern. Perfecto Paseiro Losada and his group at the University of Santiago de Compostela, in Spain, have been investigating the migration kinetics and actual migration of such compounds into a variety of types of food. They also have been carrying out studies to estimate dietary exposure. Paseiro recently spoke to LCGC about this work.

Fundamentals aspects of using HPLC techniques for protein analysis are described as they relate to the analysis of post-translational modifications (PTMs) and glycoprofiles.

The 2020 winners of the LCGC Lifetime Achievement in Chromatography Award and the Emerging Leader Award have been selected.

In HPLC Diagnostics Skills Part I we looked at baseline issues, and we continue here with HPLC peaks and in particular the skills required to identify tailing peaks, the causes of peak tailing, and most importantly, how to fix the issues that give rise to this peak deformation.

Click the title above to open the LCGC Europe November 2019 regular issue, Volume 32, Number 11, in an interactive PDF format.