Application Notes: LC
Innovations in Food Analysis — Analysis of Peptides, Additives and Flavours
December 2nd 2006The analysis of peptides and additives using a new HPLC innovative column technology, Pathfinder, was shown. For the analysis of flavours in lemon juice GC–MS with a new MS library, FFNSC, with linear retention indices was used.
Determination of Soft Drink Ingredients
December 2nd 2006Soft drink formulas often include preservatives, artificial sweeteners, flavours or caffeine in their list of ingredients. Using the Acclaim OA column, as many as eight common additives may be determined in a single run. Many of these additives are hydrophilic organic acids for which this column was designed. Notably, benzoate and sorbate, which do not resolve on C18 columns at low pH, are fully separated.
Optimizing Column Lifetime of TSK-GEL Size Exclusion Columns
December 2nd 2006Column lifetime is a more and more important issue when developing an analytical method for HPLC. Besides sample treatment, column cleaning and storage, operational parameters of the analytical method will have an influence on column lifetime. This question may not always be addressed early enough in the methods development process.
Determination of Protease Inhibitors Used in the Treatment of HIV
March 2nd 2005Protease inhibitors are a class of anti-HIV drugs used in combination therapy to block replication of the HIV virus in a person's blood. It is important to monitor the levels of these drugs in the patient since resistance can develop at low levels and at high levels the drug can exhibit toxic effects.